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Editorial Board
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IFC
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Synthesis of oncological [11C]radiopharmaceuticals for clinical PET
15 December 2011
Abstract: Positron emission tomography (PET) is a nuclear medicine modality which provides quantitative images of biological processes in vivo at the molecular level. Several PET radiopharmaceuticals ...
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Filippo Lodi,
Claudio Malizia,
Paolo Castellucci,
Gianfranco Cicoria,
Stefano Fanti,
Stefano Boschi
et al.
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447-460
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Bombesin analogues for gastrin-releasing peptide receptor imaging
20 January 2012
Abstract: Objectives: The present study describes the design and development of a series of new bombesin (BBN) antagonist peptide ligands of the form [64Cu-(NO2A-X-D-Phe6-BBN(6-13)NHEt)], where Cu-64=...
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Prasant K. Nanda,
Usha Pandey,
Brienne N. Bottenus,
Tammy L. Rold,
Gary L. Sieckman,
Ashley F. Szczodroski,
Timothy J. Hoffman,
Charles J. Smith
et al.
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461-471
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Combined-modality radioimmunotherapy: synergistic effect of paclitaxel and additive effect of bevacizumab
15 December 2011
Abstract: Introduction: This study was undertaken to investigate the effect of paclitaxel and bevacizumab on the therapeutic efficacy of 90Y-labeled B3 monoclonal antibody, directed against Ley antige...
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Beom-Su Jang,
Sang-Myung Lee,
Hyung Sub Kim,
In Soo Shin,
Faezeh Razjouyan,
Shutao Wang,
Zhengsheng Yao,
Ira Pastan,
Matthew R. Dreher,
Chang H. Paik
et al.
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472-483
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Preclinical studies of potential amyloid binding PET/SPECT ligands in Alzheimer's disease
09 January 2012
Abstract: Visualizing the neuropathological hallmarks amyloid plaques and neurofibrillary tangles of Alzheimer's disease in vivo using positron emission tomography (PET) or single photon emission comp...
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Marie M. Svedberg,
Obaidur Rahman,
Håkan Hall
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484-501
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An allogenic site-specific rat model of bone metastases for nuclear medicine and experimental oncology
15 December 2011
Abstract: Bone metastases are a major problem in several tumor entities affecting the therapeutic decision and the patient's prognosis. Single photon emission computed tomography (SPECT) and positron ...
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Barbara Biesalski,
Bengü Yilmaz,
Hans-Georg Buchholz,
Nicole Bausbacher,
Mathias Schreckenberger,
Oliver Thews
et al.
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502-508
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Influence of cations on the complexation yield of DOTATATE with yttrium and lutetium: a perspective study for enhancing the 90Y and 177Lu labeling conditions
15 December 2011
Abstract: The DOTA macrocyclic ligand can form stable complexes with many cations besides yttrium and lutetium. For this reason, the presence of competing cationic metals in yttrium-90 and lutetium-17...
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Mattia Asti,
Matteo Tegoni,
Daniela Farioli,
Michele Iori,
Claudio Guidotti,
Cathy S. Cutler,
Pat Mayer,
Annibale Versari,
Diana Salvo
et al.
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509-517
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Preclinical evaluation of anti-HER2 Affibody molecules site-specifically labeled with 111In using a maleimido derivative of NODAGA
15 December 2011
Abstract: Introduction: Affibody molecules have demonstrated potential for radionuclide molecular imaging. The aim of this study was to synthesize and evaluate a maleimido derivative of the 1,4,7-tria...
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Mohamed Altai,
Anna Perols,
Amelie Eriksson Karlström,
Mattias Sandström,
Frederic Boschetti,
Anna Orlova,
Vladimir Tolmachev
et al.
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518-529
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Synthesis and preclinical evaluation of [11C]D617, a metabolite of (R)-[11C]verapamil
09 January 2012
Abstract: Objectives: (R)-[11C]verapamil is widely used as a positron emission tomography (PET) tracer to evaluate P-glycoprotein (P-gp) functionality at the blood–brain barrier in man. A disadvantage...
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Joost Verbeek,
Stina Syvänen,
Robert C. Schuit,
Jonas Eriksson,
Elizabeth C. de Lange,
Albert D. Windhorst,
Gert Luurtsema,
Adriaan A. Lammertsma
et al.
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530-539
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Simple preparation and purification of ethanol-free solutions of 3′-deoxy-3′-[18F]fluorothymidine by means of disposable solid-phase extraction cartridges
15 December 2011
Abstract: Introduction: 3′-Deoxy-3′-[18F]fluorothymidine ([18F]FLT) shows great potential as a tracer for proliferative studies with PET. However, its regular application is often limited by low radio...
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Claudio Pascali,
Anna Bogni,
Lorenza Fugazza,
Claudio Cucchi,
Ornella Crispu,
Luca Laera,
Ren Iwata,
Greta Maiocchi,
Flavio Crippa,
Emilio Bombardieri
et al.
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540-550
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An automated module for the separation and purification of cyclotron-produced 99mTcO4−
09 January 2012
Abstract: Introduction: The shortage of reactor-produced molybdenum-99 (99Mo, t½=66 h) has renewed interest in alternative production methods of its daughter isotope, technetium-99m (99mTc, t½=6.02 h)...
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Thomas J. Morley,
Maurice Dodd,
Katherine Gagnon,
Vicky Hanemaayer,
John Wilson,
Stephen A. McQuarrie,
Wade English,
Thomas J. Ruth,
François Bénard,
Paul Schaffer
et al.
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551-559
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68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers
15 December 2011
Abstract: Introduction: The urokinase-type plasminogen activator receptor (uPAR) is a well-established biomarker for tumor aggressiveness and metastatic potential. DOTA-AE105 and DOTA-AE105-NH2 labele...
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Morten Persson,
Jacob Madsen,
Søren Østergaard,
Michael Ploug,
Andreas Kjaer
et al.
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560-569
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Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation
15 December 2011
Abstract: Introduction: The translocator protein 18 kDa (TSPO), although minimally expressed in healthy brain, is up-regulated in pathological conditions, coinciding with microglial activation. It is ...
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Nicolas Arlicot,
Johnny Vercouillie,
Maria-João Ribeiro,
Clovis Tauber,
Yann Venel,
Jean-Louis Baulieu,
Serge Maia,
Philippe Corcia,
Michael G. Stabin,
Aaron Reynolds,
Michael Kassiou,
Denis Guilloteau
et al.
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570-578
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Synthesis, radiolabeling, biodistribution and fluorescent imaging of histidine-coupled hematoporphyrin
09 January 2012
Abstract: Introduction: Hematoporphyrin (Hp) and hematoporphyrin derivatives (HpDs) have been widely used as photosensitizers in photodynamic therapy (PDT). Radiolabeling of HpDs is helpful for precli...
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Yupeng Liu,
Bo Shen,
Fei Liu,
Bin Zhang,
Taiwei Chu,
Jing Bai,
Shanglian Bao
et al.
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579-585
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Evaluation of an automated double-synthesis module: efficiency and reliability of subsequent radiosyntheses of FHBG and FLT
15 December 2011
Abstract: We optimized the synthesis methods for 3′-deoxy-3′-[18F]fluorothymidine ([18F]FLT) and 9-(4-[18F]fluoro-3-[hydroxymethyl]butyl)guanine) ([18F]FHBG) and automated them on an Explora General N...
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Sabrina Niedermoser,
Manuela Pape,
Franz Josef Gildehaus,
Carmen Wängler,
Markus Hartenbach,
Ralf Schirrmacher,
Peter Bartenstein,
Björn Wängler
et al.
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586-592
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Synthesis and preliminary evaluation of [18F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB2 receptor
09 January 2012
Abstract: Introduction: The cannabinoid receptor type 2 (CB2) is an important target for development of drugs and imaging agents for diseases, such as neuroinflammation, neurodegeneration and cancer. ...
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Nashaat Turkman,
Aleksander Shavrin,
Vincenzo Paolillo,
Hsin Hsien Yeh,
Leo Flores,
Suren Soghomonian,
Brian Rabinovich,
Andrei Volgin,
Juri Gelovani,
Mian Alauddin
et al.
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593-600
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Table of Contents
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IBC
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