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Editorial Board
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IFC
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Synthesis and evaluation of [18F]exendin (9–39) as a potential biomarker to measure pancreatic β-cell mass
28 October 2011
Abstract: Introduction: Glucagon-like peptide 1 (GLP-1) is released in response to food intake and plays an important role in maintaining blood glucose homeostasis. Exendin (9–39), a potent glucagon-l...
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Yi Wang,
Keunpoong Lim,
Marc Normandin,
Xiaojian Zhao,
Gary W. Cline,
Yu-Shin Ding
et al.
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167-176
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Radiolabeled Cu-ATSM as a novel indicator of overreduced intracellular state due to mitochondrial dysfunction: studies with mitochondrial DNA-less ρ0 cells and cybrids carrying MELAS mitochondrial DNA mutation
28 October 2011
Abstract: Objectives: Radiolabeled Cu-diacetyl-bis (N4-methylthiosemicarbazone) (⁎Cu-ATSM), including 60/62/64Cu-ATSM, is a potential imaging agent of hypoxic tumors for positron emission tomography (...
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Yukie Yoshii,
Makoto Yoneda,
Masamichi Ikawa,
Takako Furukawa,
Yasushi Kiyono,
Tetsuya Mori,
Hiroshi Yoshii,
Nobuyuki Oyama,
Hidehiko Okazawa,
Tsuneo Saga,
Yasuhisa Fujibayashi
et al.
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177-185
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Evaluation of copper-64-labeled somatostatin agonists and antagonist in SSTr2-transfected cell lines that are positive and negative for p53: implications for cancer therapy
07 November 2011
Abstract: Objectives: Radiolabeled somatostatin analogs have become important agents for molecular imaging and targeted radiotherapy of somatostatin receptor-positive tumors. Here we determine the eff...
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Kim Nguyen,
Jesse J. Parry,
Buck E. Rogers,
Carolyn J. Anderson
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187-197
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PET study using [11C]FTIMD with ultra-high specific activity to evaluate I2-imidazoline receptors binding in rat brains
28 September 2011
Abstract: Introduction: We recently developed a selective 11C-labeled I2-imidazoline receptor (I2R) ligand, 2-(3-fluoro-4-[11C]tolyl)-4,5-dihydro-1H-imidazole ([11C]FTIMD). [11C]FTIMD showed specific ...
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Kazunori Kawamura,
Yuichi Kimura,
Joji Yui,
Hidekatsu Wakizaka,
Tomoteru Yamasaki,
Akiko Hatori,
Katsushi Kumata,
Masayuki Fujinaga,
Yuichiro Yoshida,
Masanao Ogawa,
Nobuki Nengaki,
Toshimitsu Fukumura,
Ming-Rong Zhang
et al.
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199-206
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Studies of the myocardial uptake and excretion mechanisms of a novel 99mTc heart perfusion agent
14 November 2011
Abstract: Introduction: 99mTc-TMEOP is a novel heart perfusion radiotracer exhibiting high initial and persistent heart uptake associated with rapid blood and liver clearance. This study aimed at dete...
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Filipa Mendes,
Lurdes Gano,
Célia Fernandes,
António Paulo,
Isabel Santos
et al.
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207-213
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Usefulness of [18F]-DA and [18F]-DOPA for PET imaging in a mouse model of pheochromocytoma
28 September 2011
Abstract: Purpose: To evaluate the usefulness of [18F]-6-fluorodopamine ([18F]-DA) and [18F]-L-6-fluoro-3,4-dihydroxyphenylalanine ([18F]-DOPA) positron emission tomography (PET) in the detection of s...
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Lucia Martiniova,
Susannah Cleary,
Edwin W. Lai,
Dale O. Kiesewetter,
Jurgen Seidel,
Linda F. Dawson,
Jacqueline K. Phillips,
David Thomasson,
Xiaoyuan Chen,
Graeme Eisenhofer,
James F. Powers,
Richard Kvetnansky,
Karel Pacak
et al.
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215-226
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Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling: Part I: PET studies
28 October 2011
Abstract: Background: LBT-999 (E)-N-(4-fluorobut-2-enyl)-2β-carbomethoxy-3β-(4′-tolyl)nortropane is a dopamine transporter (DAT) ligand. [18F]LBT-999 was first labelled with carbon-11; we will now des...
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Wadad Saba,
Marie-Anne Peyronneau,
Frédéric Dollé,
Sébastien Goutal,
Michel Bottlaender,
Héric Valette
et al.
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227-233
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Synthesis and evaluation of a C-6 alkylated pyrimidine derivative for the in vivo imaging of HSV1-TK gene expression
28 September 2011
Abstract: Introduction: We report on the synthesis, radiolabeling, in vitro and in vivo characterization of N-Me-[18F]FHBT (6-(3-[18F]fluoro-2-(hydroxymethyl)propyl)-1,5-dimethylpyrimidin-2,4(1H,3H)-d...
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Ursina Müller,
Miljen Martić,
Tatjana Gazivoda Kraljević,
Svjetlana Krištafor,
Tobias L. Ross,
Charlene Ranadheera,
Adrienne Müller,
Mariana Born,
Stefanie D. Krämer,
Silvana Raić-Malić,
Simon M. Ametamey
et al.
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235-246
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Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents
14 November 2011
Abstract: Introduction: The overexpression of epidermal growth factor receptor (EGFR) in tumors underlines the recent interest in EGFR as attractive target for the development of new cancer imaging ag...
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Carina Neto,
Célia Fernandes,
Maria Cristina Oliveira,
Lurdes Gano,
Filipa Mendes,
Torsten Kniess,
Isabel Santos
et al.
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247-260
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Nonlinear compartmental model of 18F-choline
02 December 2011
Abstract: Introduction: This work develops a compartmental model of 18F-choline in order to evaluate its biokinetics and so to describe the temporal variation of the radiopharmaceuticals' uptake in an...
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Federico Tavola,
Tilman Janzen,
Augusto Giussani,
Danya Facchinetti,
Ivan Veronese,
Helena Uusijärvi-Lizana,
Soren Mattsson,
Christoph Hoeschen,
Marie Claire Cantone
et al.
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261-268
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Enhanced antiproliferative effects of combination hexokinase II shRNA and NIS gene therapy on vascular smooth muscle cells
28 September 2011
Abstract: Introduction: This study was designed to determine the antiproliferative effects of combination gene therapy using sodium iodide symporter (NIS)-based radioiodine and lentivirus-mediated sho...
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Mi-Hye Hwang,
Sang-Woo Lee,
Jung Eun Kim,
Ho Won Lee,
Yong Hyun Jeon,
Jeoung-Hee Ha,
Byeong-Cheol Ahn,
Jaetae Lee
et al.
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269-278
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Characterization of 4-[18F]-ADAM as an imaging agent for SERT in non-human primate brain using PET: a dynamic study
02 December 2011
Abstract: Introduction: Serotonin transporter (SERT) has been associated with many psychiatric diseases. This study investigated the biodistribution of a serotonin transporter imaging agent, N,N-dimet...
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Yu-An Chen,
Wen-Sheng Huang,
Yaoh-Shiang Lin,
Cheng-Yi Cheng,
Ren-Shyan Liu,
Shyh-Jen Wang,
I-Hsun Li,
San-Yuan Huang,
Chyng-Yann Shiue,
Cheng-Yu Chen,
Kuo-Hsing Ma
et al.
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279-285
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[11C]Acetate rest–stress protocol to assess myocardial perfusion and oxygen consumption reserve in a model of congestive heart failure in rats
14 November 2011
Abstract: This study describes an [11C]acetate rest–stress method to obtain an indirect estimate of myocardial blood flow (MBF) and myocardial oxygen consumption (MVO2) in rats. Doxorubicin cardiotoxi...
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Etienne Croteau,
Suzanne Gascon,
M'hamed Bentourkia,
Réjean Langlois,
Jacques A. Rousseau,
Roger Lecomte,
François Bénard
et al.
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287-294
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Simplified quantification and whole-body distribution of [18F]FE-PE2I in nonhuman primates: prediction for human studies
28 October 2011
Abstract: Introduction: [18F]FE-PE2I is a promising dopamine transporter (DAT) radioligand. In nonhuman primates, we examined the accuracy of simplified quantification methods and the estimates of rad...
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Andrea Varrone,
Balázs Gulyás,
Akihiro Takano,
Michael G. Stabin,
Cathrine Jonsson,
Christer Halldin
et al.
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295-303
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Radiation dose estimates for carbon-11-labelled PET tracers
28 October 2011
Abstract: Introduction: Carbon-11-labelled positron emission tomography (PET) tracers commonly used in biomedical research expose subjects to ionising radiation. Dosimetry is the measurement of radiat...
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Jasper van der Aart,
William A. Hallett,
Eugenii A. Rabiner,
Jan Passchier,
Robert A. Comley
et al.
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305-314
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