Nuclear Medicine and Biology
Volume 38, Issue 1 , Pages 39-51 , January 2011

Radiosynthesis and pre-clinical evaluation of [18F]fluoro-[1,2-2H4]choline

  • Graham Smith

      Affiliations

    • Comprehensive Cancer Imaging Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • ,
  • Yongjun Zhao

      Affiliations

    • MDx Discovery (part of GE Healthcare) at Hammersmith Imanet, Ltd., Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • ,
  • Julius Leyton

      Affiliations

    • Comprehensive Cancer Imaging Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • ,
  • Bo Shan

      Affiliations

    • MDx Discovery (part of GE Healthcare) at Hammersmith Imanet, Ltd., Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • ,
  • Quang-de Nguyen

      Affiliations

    • Comprehensive Cancer Imaging Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • ,
  • Meg Perumal

      Affiliations

    • Comprehensive Cancer Imaging Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • ,
  • David Turton

      Affiliations

    • GE-Imanet, Hammersmith Hospital, Du Cane Road, London, W12 0NN, United Kingdom
    • ,
  • Erik Årstad

      Affiliations

    • MDx Discovery (part of GE Healthcare) at Hammersmith Imanet, Ltd., Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • ,
  • Sajinder K. Luthra

      Affiliations

    • MDx Discovery (part of GE Healthcare) at Hammersmith Imanet, Ltd., Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • ,
  • Edward G. Robins

      Affiliations

    • MDx Discovery (part of GE Healthcare) at Hammersmith Imanet, Ltd., Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • ,
  • Eric O. Aboagye

      Affiliations

    • Comprehensive Cancer Imaging Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
    • Corresponding Author InformationCorresponding author. Tel.: +44 208 383 3759; fax: +44 208 383 1783.

Received 19 May 2009 ,Revised 14 June 2010 ,Accepted 14 June 2010.

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☆ Funding provided by CR-UK&EPSRC Cancer Imaging Centre at Imperial College, London, in association with the MRC and Department of Health (England) grant C2536/A10337 and UK Medical Research Council core funding grant U.1200.02.005.00001.01.

PII: S0969-8051(10)00325-2

doi: 10.1016/j.nucmedbio.2010.06.012

Nuclear Medicine and Biology
Volume 38, Issue 1 , Pages 39-51 , January 2011

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