Nuclear Medicine and Biology
Volume 38, Issue 1 , Pages 129-136, January 2011

A kit to prepare 111In-DTPA-trastuzumab (Herceptin) Fab fragments injection under GMP conditions for imaging or radioimmunoguided surgery of HER2-positive breast cancer☆

  • Deborah A. Scollard

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • ,
  • Conrad Chan

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • ,
  • Claire M.B. Holloway

      Affiliations

    • Department of Surgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 1H1
    • ,
  • Raymond M. Reilly

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • Department of Medical Imaging, University of Toronto, Toronto, ON, Canada M5S 3E2
    • Toronto General Research Institute, University Health Network, Toronto, ON, Canada M5G 2M9
    • Corresponding Author InformationCorresponding author. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada M5S 3M2. Tel.: +1 416 946 5522; fax: +1 416 978 8511.

Received 9 January 2010; received in revised form 2 June 2010; accepted 30 June 2010. published online 02 September 2010.

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☆ This study was supported by grants to C.H. (No. 05NOV00176) and R.M.R. (1 mm Challenge) from the Ontario Institute of Cancer Research with funds from the Province of Ontario.

PII: S0969-8051(10)00323-9

doi:10.1016/j.nucmedbio.2010.06.010

Nuclear Medicine and Biology
Volume 38, Issue 1 , Pages 129-136, January 2011

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