Nuclear Medicine and Biology
Volume 37, Issue 4 , Pages 433-438 , May 2010

Investigation of the pharmacokinetics of 3′-deoxy-3′-[18F]fluorothymidine uptake in the bone marrow before and early after initiation of chemoradiation therapy in head and neck cancer

  • Yusuf Menda

      Affiliations

    • Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 319 356 3214; fax: +1 319 356 2220.
    • ,
  • Laura L. Boles Ponto

      Affiliations

    • Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • Kenneth J. Dornfeld

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • Timothy J. Tewson

      Affiliations

    • Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • G. Leonard Watkins

      Affiliations

    • Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • Anjali K. Gupta

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • Carryn Anderson

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • Sarah McGuire

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • Michael K. Schultz

      Affiliations

    • Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • John J. Sunderland

      Affiliations

    • Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • Michael M. Graham

      Affiliations

    • Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    • ,
  • John M. Buatti

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA

Received 5 November 2009 ,Revised 20 February 2010 ,Accepted 28 February 2010.

References 

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  3. Menda Y, Boles Ponto LL, Dornfeld KJ, Tewson TJ, Watkins GL, Schultz MK, et al. Kinetic analysis of 3′-deoxy-3′-18F-fluorothymidine (18F-FLT) in head and neck cancer patients before and early after initiation of chemoradiation therapy. J Nucl Med. 2009;50:1028–1035
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☆ Part of this study was presented at the Academy of Molecular Imaging/Society for Molecular Imaging Joint Molecular Imaging Conference 2007 in Providence, RI, and at the Society of Nuclear Medicine 2009 Annual Meeting in Toronto, Ontario, Canada.

PII: S0969-8051(10)00030-2

doi: 10.1016/j.nucmedbio.2010.02.005

Nuclear Medicine and Biology
Volume 37, Issue 4 , Pages 433-438 , May 2010

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