Investigation of the pharmacokinetics of 3′-deoxy-3′-[18F]fluorothymidine uptake in the bone marrow before and early after initiation of chemoradiation therapy in head and neck cancer

Menda, Yusuf; Boles Ponto, Laura L.; Dornfeld, Kenneth J.; Tewson, Timothy J.; Watkins, G. Leonard; Gupta, Anjali K.; Anderson, Carryn; McGuire, Sarah; Schultz, Michael K.; Sunderland, John J.; Graham, Michael M.; Buatti, John M.

doi:10.1016/j.nucmedbio.2010.02.005

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Volume 37, Issue 4 , Pages 433-438, May 2010

Investigation of the pharmacokinetics of 3′-deoxy-3′-[¹⁸F]fluorothymidine uptake in the bone marrow before and early after initiation of chemoradiation therapy in head and neck cancer☆

Yusuf Menda
- Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
- Corresponding author. Tel.: +1 319 356 3214; fax: +1 319 356 2220.
Laura L. Boles Ponto
- Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Kenneth J. Dornfeld
- Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Timothy J. Tewson
- Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
G. Leonard Watkins
- Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Anjali K. Gupta
- Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Carryn Anderson
- Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Sarah McGuire
- Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Michael K. Schultz
- Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
John J. Sunderland
- Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
Michael M. Graham
- Division of Nuclear Medicine, Department of Radiology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
John M. Buatti
- Department of Radiation Oncology, University of Iowa Hospitals and Clinics Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA

Received 5 November 2009; received in revised form 20 February 2010; accepted 28 February 2010.

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☆ Part of this study was presented at the Academy of Molecular Imaging/Society for Molecular Imaging Joint Molecular Imaging Conference 2007 in Providence, RI, and at the Society of Nuclear Medicine 2009 Annual Meeting in Toronto, Ontario, Canada.

PII: S0969-8051(10)00030-2

doi:10.1016/j.nucmedbio.2010.02.005

« Previous Next »Nuclear Medicine and Biology
Volume 37, Issue 4 , Pages 433-438, May 2010

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