Nuclear Medicine and Biology
Volume 37, Issue 3 , Pages 245-253 , April 2010

MONICA: a compact, portable dual gamma camera system for mouse whole-body imaging

  • Wenze Xi

      Affiliations

    • Science Applications International Corporation (SAIC)-Frederick, Frederick, MD, USA
    • Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1088, USA
    • ,
  • Jurgen Seidel

      Affiliations

    • Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1088, USA
    • Contractor to SAIC-Frederick, Frederick, MD, USA
    • ,
  • John W. Kakareka

      Affiliations

    • Signal Processing and Instrumentation Section, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA
    • ,
  • Thomas J. Pohida

      Affiliations

    • Signal Processing and Instrumentation Section, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA
    • ,
  • Diane E. Milenic

      Affiliations

    • Radioimmune & Inorganic Chemistry Section, Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    • ,
  • James Proffitt

      Affiliations

    • Adaptive I/O Technologies, Blacksburg, VA, USA
    • ,
  • Stan Majewski

      Affiliations

    • Department of Radiology, West Virginia University, Morgantown, WV, USA
    • ,
  • Andrew G. Weisenberger

      Affiliations

    • Radiation Detectors and Imaging Group, Thomas Jefferson National Accelerator Facility, Newport News, VA, USA
    • ,
  • Michael V. Green

      Affiliations

    • Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1088, USA
    • Contractor to SAIC-Frederick, Frederick, MD, USA
    • ,
  • Peter L. Choyke

      Affiliations

    • Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1088, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 301 402 8409; fax: +1 301 402 3191.

Received 28 September 2009 ,Revised 2 December 2009 ,Accepted 3 December 2009.

References 

  1. Proffitt J, Hammond W, Majewski S, et al. A Flexible High-rate USB2 Data Acquisition System for PET and SPECT Imaging. IEEE Nucl Sci Symp Conf Rec. 2005;5:2971–2975
  2. Giusti RM, Shastri KA, Cohen MH, Keegan P, Pazdur R. FDA Drug Approval Summary: Panitumumab (Vectibix). Oncologist. 2007;12:577–583
  3. Ray GL, Baidoo KE, Wong KJ, et al. Preclinical evaluation of a monoclonal antibody targeting the epidermal growth factor receptor as a radioimmunodiagnostic and radioimmunotherapeutic agent. Br J Pharmacol. 2009;157(8):1541–1548
  4. Loudos G, Majewski S, Wojcik R, et al. Performance evaluation of a dedicated camera suitable for dynamic radiopharmaceutical evaluation in small animals. IEEE Trans Nucl Sci. 2007;50:454–460
  5. T-QuestTM gamma camera product information. MEDX, Inc., Arlington Heights (Ill). http://www.medx-inc.com/tquest.html.
  6. Kiyono Y, Kuge Y, Katada Y, Kawashima H, Magata Y, Sajj H. Applicability of a high-resolution small semiconductor gamma camera to small animal imaging. Nucl Med Commun. 2007;28:736–741
  7. Yamamoto S, Hatazawa J. Development of a small FOV LaBr3(Ce) gamma camera for low energy single photon imaging. J Nucl Med. 2007;48(Suppl 2):94P
  8. Pani R, Pellegrini R, Cinti MN, et al. New devices for imaging in nuclear medicine. Cancer Biother Radiopharm. 2004;19:121–128
  9. Notaristefani FD, Pani R, Scopinaro F, et al. First results from a YAP:Ce gamma camera for small animal studies. IEEE Trans Nucl Sci. 1996;43:3264–3271

☆ Animal Care: Animal care was provided in accordance with the procedures outlined in the “Guide for Care and Use of Laboratory Animals” (National Research Council; 1996; National Academy Press; Washington, D.C.).

☆☆ Financial support: This project has been funded in whole or in part with federal funds from the National Cancer Institute, National Institutes of Health, under contract HHSN261200800001E. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products or organizations imply endorsement by the U.S. Government.

PII: S0969-8051(09)00293-5

doi: 10.1016/j.nucmedbio.2009.12.003

Nuclear Medicine and Biology
Volume 37, Issue 3 , Pages 245-253 , April 2010

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