Nuclear Medicine and Biology
Volume 37, Issue 2 , Pages 215-226, February 2010

Multispecies animal investigation on biodistribution, pharmacokinetics and toxicity of 177Lu-EDTMP, a potential bone pain palliation agent

  • Domokos Máthé

      Affiliations

    • Department of Applied Radioisotopes and Animal Experimentation, National ‘Frédéric Joliot-Curie’ Institute of Radiobiology and Radiohygiene, H-1221 Budapest, Hungary
    • Corresponding Author InformationCorresponding author. Tel.: +36 1 482 2012; fax: +36 1 482 2007.
  • ,
  • Lajos Balogh

      Affiliations

    • Department of Applied Radioisotopes and Animal Experimentation, National ‘Frédéric Joliot-Curie’ Institute of Radiobiology and Radiohygiene, H-1221 Budapest, Hungary
  • ,
  • András Polyák

      Affiliations

    • Department of Applied Radioisotopes and Animal Experimentation, National ‘Frédéric Joliot-Curie’ Institute of Radiobiology and Radiohygiene, H-1221 Budapest, Hungary
  • ,
  • Réka Király

      Affiliations

    • Department of Applied Radioisotopes and Animal Experimentation, National ‘Frédéric Joliot-Curie’ Institute of Radiobiology and Radiohygiene, H-1221 Budapest, Hungary
  • ,
  • Teréz Márián

      Affiliations

    • Institute of Nuclear Medicine, Debrecen University, Debrecen, Hungary
  • ,
  • Dariusz Pawlak

      Affiliations

    • Institute of Atomic Energy, Radioisotope Centre POLATOM, Swierk-Otwock, Poland
  • ,
  • John J. Zaknun

      Affiliations

    • International Atomic Energy Agency (IAEA), Vienna, Austria
  • ,
  • Maroor R.A. Pillai

      Affiliations

    • International Atomic Energy Agency (IAEA), Vienna, Austria
  • ,
  • Győző A. Jánoki

      Affiliations

    • Department of Applied Radioisotopes and Animal Experimentation, National ‘Frédéric Joliot-Curie’ Institute of Radiobiology and Radiohygiene, H-1221 Budapest, Hungary

Received 14 May 2009; received in revised form 15 August 2009; accepted 28 September 2009. published online 13 November 2009.

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 Part of this work was conducted under an International Atomic Energy Agency (IAEA) Coordinated Research Project and a European Commission FP6 grant to the European Molecular Imaging Laboratories (LSH-CT 2004-503569).

PII: S0969-8051(09)00242-X

doi:10.1016/j.nucmedbio.2009.09.004

Nuclear Medicine and Biology
Volume 37, Issue 2 , Pages 215-226, February 2010