Nuclear Medicine and Biology
Volume 37, Issue 1 , Pages 35-40 , January 2010

Radiosynthesis and ex vivo evaluation of (R)-(−)-2-chloro-N-[1-11C-propyl]n-propylnorapomorphine

  • Mikael Palner

      Affiliations

    • Neurobiology Research Unit, Rigshospitalet, University of Copenhagen, DK-2300, Copenhagen, Denmark
    • Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark
    • Corresponding Author InformationCorresponding author. Neurobiology Research Unit, Rigshospitalet, DK-2100 Copenhagen, Denmark. Tel.: +45 3545 6704; fax: +45 3545 6713.
    • ,
  • Patrick McCormick

      Affiliations

    • PET Centre, Centre for Addiction and Mental Health, M5T 1RB, Toronto, ON, Canada
    • ,
  • Nic Gillings

      Affiliations

    • Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark
    • PET and Cyclotron Unit, Rigshospitalet, DK-2300, Copenhagen, Denmark
    • ,
  • Mikael Begtrup

      Affiliations

    • Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark
    • Institute for Medicinal Chemistry, Pharmaceutical Faculty, University of Copenhagen, DK-2300, Copenhagen, Denmark
    • ,
  • Alan A. Wilson

      Affiliations

    • PET Centre, Centre for Addiction and Mental Health, M5T 1RB, Toronto, ON, Canada
    • ,
  • Gitte M. Knudsen

      Affiliations

    • Neurobiology Research Unit, Rigshospitalet, University of Copenhagen, DK-2300, Copenhagen, Denmark
    • Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark

Received 13 March 2009 ,Revised 4 August 2009 ,Accepted 23 August 2009.

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☆ This work was supported by the Danish Agency for Science, Technology and Innovation; Rigshospitalet; the EC-FP6-project DiMI, LSHB-CT-2005-512146; the Centre of Addiction and Mental Health in Toronto, Canada; and the Lundbeck Foundation, Denmark. Ki determinations were generously performed by the National Institute of Mental Health's Psychoactive Drug Screening Program (NIMH PDSP), contract no. NO1MH32004.

PII: S0969-8051(09)00216-9

doi: 10.1016/j.nucmedbio.2009.08.005

Nuclear Medicine and Biology
Volume 37, Issue 1 , Pages 35-40 , January 2010

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