Nuclear Medicine and Biology
Volume 36, Issue 7 , Pages 811-819 , October 2009

In vivo monitoring of intranuclear p27kip1 protein expression in breast cancer cells during trastuzumab (Herceptin) therapy

  • Bart Cornelissen

      Affiliations

    • Division of Nuclear Medicine, University Health Network, Toronto, ON, Canada M5S 3E2
    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • MRC/CRUK Gray Institute for Radiation Oncology and Biology, Oxford University, OX3 7LJ Oxford, UK
    • Corresponding Author InformationCorresponding author. Gray Institute for Radiation Oncology and Biology, Radiobiology Research Institute, Churchill Hospital, Headington, OX3 7LJ Oxford, UK.
    • ,
  • Veerle Kersemans

      Affiliations

    • Division of Nuclear Medicine, University Health Network, Toronto, ON, Canada M5S 3E2
    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • ,
  • Kristin McLarty

      Affiliations

    • Division of Nuclear Medicine, University Health Network, Toronto, ON, Canada M5S 3E2
    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • ,
  • Lara Tran

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • ,
  • Katherine A. Vallis

      Affiliations

    • MRC/CRUK Gray Institute for Radiation Oncology and Biology, Oxford University, OX3 7LJ Oxford, UK
    • ,
  • Raymond M. Reilly

      Affiliations

    • Division of Nuclear Medicine, University Health Network, Toronto, ON, Canada M5S 3E2
    • Department of Medical Imaging, University of Toronto, Toronto, ON, Canada M5S 3E2
    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2

Received 26 January 2009 ,Revised 28 April 2009 ,Accepted 10 May 2009.

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☆ This study was supported by grants from the Ontario Cancer Research Network (No. 03-NOV-0428 and 1 mm Cancer Challenge) with funds from the Province of Ontario.

PII: S0969-8051(09)00127-9

doi: 10.1016/j.nucmedbio.2009.05.003

Nuclear Medicine and Biology
Volume 36, Issue 7 , Pages 811-819 , October 2009

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