Radiosynthesis of [131I]IAZGP via nucleophilic substitution and its biological evaluation as a hypoxia marker — is specific activity a factor influencing hypoxia-mapping ability of a hypoxia marker?

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Volume 36, Issue 5 , Pages 477-487, July 2009

Radiosynthesis of [¹³¹I]IAZGP via nucleophilic substitution and its biological evaluation as a hypoxia marker — is specific activity a factor influencing hypoxia-mapping ability of a hypoxia marker?

Makiko Suehiro
- Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
- Corresponding author. Tel.: +1 646 888 2153; fax: +1 212 639 2611.
Paul Burgman
- Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Sean Carlin
- Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Sean Burke
- Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Guangbin Yang
- Organic Synthesis Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Ouathek Ouerfelli
- Organic Synthesis Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Christoph Oehler-Janne
- Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Joseph O'Donoghue
- Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Clifton Ling
- Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
John Humm
- Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA