« Previous
Next »
Nuclear Medicine and Biology
Volume 36, Issue 4
, Pages 403-409
, May 2009
Development of microwave-based automated nucleophilic [18F]fluorination system and its application to the production of [18F]flumazenil
References
- . Fast chemistry in microwave fields: nucleophilic 18F-radiofluorinations of aromatic molecules. Appl Radiat Isot. 1993;44(5):889–893
- . Microwave-enhanced radiochemistry. Chem Soc Rev. 2000;29:239–249
- . Microwave applications in radiolabelling with short-lived positron emitting radionuclides. J Label Compd Radiopharm. 2002;45:715–746
- . Improving the yield of 2-[18F]fluoro-2-deoxyglucose using a microwave cavity. Nucl Med Biol. 1996;23:605–609
- . Microwave synthesis (chemistry at the speed of light). North Carolina: CEM publishing; 2002;
- Radioligands for PET studies of central benzodiazepine receptors and PK (peripheral benzodiazepine) binding sites — current status. Nucl Med Biol. 1993;20:503–525
- Clinical utility of flumazenil-PET versus [18F]fluorodeoxyglucose-PET and MRI in refractory partial epilepsy. Brain. 1998;121:2067–2081
- . Decreased brain GABAA-benzodiazepine receptor binding in panic disorder. Arch Gen Psychiatry. 1998;55:715–720
- Positron emission tomography measures of benzodiazepine receptors in Huntington’s disease. Ann Neurol. 1993;34(1):76–81
- Permanent cortical damage detected by flumazenil positron emission tomography in acute stroke. Stroke. 1998;29(2):454–461
- Early [11C]flumazenil/H2O positron emission tomography predicts irreversible ischemic cortical damage in stroke patients receiving acute thrombolytic therapy. Stroke. 2000;31(2):366–369
- Preparation of highly specific radioactivity [18F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography. Nucl Med Biol. 2005;32:109–116
- [18F]Flumazenil for central benzodiazepine receptor imaging and its comparison with [11C] in human brain. J Nucl Med. 2007;48:61P
- . Isotopic 18F/19F exchange in the flumazenil molecule using K18F/Kryptofix complex. J Label Compd Radiopharm. 2003;46:S213
- . Preparation of [18F]flumazenil, a potential radioligand for PET imaging of central benzodiazepine receptors by isotope exchange. Radiochemistry. 2004;46(3):290–294
- . Optimization of nucleophilic fluorination step in the synthesis of various compounds labeled with fluorine-18 for their use as PET radiotracers. J Label Compd Radiopharm. 2001;44:S895–S897
- Development of a small animal PET scanner using DOI detectors. IEEE Trans Nucl Sci. 2008;55(3):906–911
- . Water-insoluble drug formulation. 2nd ed. Florida: CRC Press; 2008;
- . Benzodiazepine receptor binding in vivo with [3H]-Ro 15-1788. Life Sci. 1985;37:345–355
PII: S0969-8051(09)00038-9
doi: 10.1016/j.nucmedbio.2009.01.011
© 2009 Elsevier Inc. All rights reserved.
« Previous
Next »
Nuclear Medicine and Biology
Volume 36, Issue 4
, Pages 403-409
, May 2009
