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Nuclear Medicine and Biology
Volume 36, Issue 4
, Pages 427-433
, May 2009
The effect of PPAR-γ agonist on 18F-FDG uptake in tumor and macrophages and tumor cells
References
- . The steroid and thyroid hormone receptor superfamily. Science. 1988;240:889–895
- . Adipogenesis and obesity: rounding out the big picture. Cell. 1996;87:377–389
- . Thiazolidinediones. N Engl J Med. 2004;351:1106–1118
- Distinct properties and advantages of a novel peroxisome proliferator-activated receptor [gamma] selective modulator. Mol Endocrinol. 2003;17:662–676
- . Inflammation. Signaling the fat controller. Nature. 1996;384:23–24
- . Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology. 1996;137:354–366
- Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages. J Biol Chem. 1998;273:25573–25580
- . Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm Res. 2000;49:497–505
- . The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. J Immunol. 2000;164:1364–1371
- Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-12 production in murine dendritic cells. FEBS Lett. 2000;486:261–266
- Peroxisome proliferator-activated receptor gamma activators affect the maturation of human monocyte-derived dendritic cells. Eur J Immunol. 2001;31:2857–2865
- . Macrophages in human atheroma contain PPAR-gamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma (PPAR-gamma) expression and reduction of MMP-9 activity through PPAR-gamma activation in mononuclear phagocytes in vitro. Am J Pathol. 1998;153:17–23
- Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonists. PPAR-gamma co-association with transcription factor NFAT. J Biol Chem. 2000;275:4541–4544
- . The peroxisome proliferators activated receptor-γ is a negative regulator of macrophages activation. Nature. 1998;391:79–82
- . PPAR-γ Agonists inhibit the production of monocyte inflammatory cytokines. Nature. 1998;391:82–86
- . Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes. Science. 1987;235:1492–1495
- High [18F]- fluorodeoxyglucose uptake in abdominal abscesses: a PET study. J Comput Assist Tomogr. 1989;13:829–831
- Ringlike uptake of [18F]FDG in brain abscess: a PET study. J Comput Assist Tomogr. 1990;14:486–487
- . Uptake of fluorine-18-fluorodeoxyglucose in sarcoidosis. J Nucl Med. 1994;35:1647–1649
- FDG-PET in infectious lesions: the detection and assessment of lesion activity. Ann Nucl Med. 1996;10:185–191
- FDG-PET in the selection of brain lesions for biopsy. J Comput Assist Tomogr. 1991;15:796–801
- . Discordance between F-18 fluorodeoxyglucose uptake and contrast enhancement in a brain abscess. Clin Nucl Med. 1993;18:682–684
- . Rapid detection of human infections with fluorine-18 fluorodeoxyglucose and positron emission tomography: preliminary results. Eur J Nucl Med. 1998;25:1238–1243
- . Uptake of positron emission tomography tracers in experimental bacterial infections: a comparative biodistribution study of radiolabeled FDG, thymidine, l-methionine, 67Ga-citrate and 125I-HSA. Eur J Nucl Med. 1999;26:333–341
- . High accumulation of fluorine-18-fluorodeoxyglucose in turpentine-induced inflammatory tissue. J Nucl Med. 1995;36:1301–1306
- . Overexpression of folate binding protein in ovarian cancers. Int J Cancer. 1997;74:193–197
- FDG Uptake and glucose transporter subtype expressions in experimental tumor and inflammation model. J Nucl Med. 2001;42:1551–1555
- . Expression of glucose transporters in head-and-neck tumors. Int J Cancer. 1994;56:622–629
- Correlation of FDG-PET imaging with Glut-1 and Glut-3 expression in early-stage non-small cell lung cancer. Lung Cancer. 2001;33:99–107
- Expression of glucose transporters in human pancreatic tumors compared with increased FDG accumulation in PET study. J Nucl Med. 1997;38:1337–1344
- FDG Uptake, Glut-1 glucose transporter and cellularity in human pancreatic tumors. J Nucl Med. 1998;39:1727–1735
- Correlation of Glut-1 glucose transporter expression with [18F]FDG uptake in non-small cell lung cancer. Eur J Nucl Med. 2000;27:1778–1785
- Correlation of GLUT-1 overexpression, tumor size, and depth of invasion with 18F-2-fluoro-2-deoxy-d-glucose uptake by positron emission tomography in colorectal cancer. Dig Dis Sci. 2006;51:2198–2205
- . Glut-1 expression and enhanced glucose metabolism are associated with tumour grade in bone and soft tissue sarcomas: a prospective evaluation by [18F]fluorodeoxyglucose positron emission tomography. Eur J Nucl Med Mol Imaging. 2006;33:683–691
- . Expression of Glut-1 and Glut-3 in untreated oral squamous cell carcinoma compared with FDG accumulation in a PET study. Eur J Nucl Med Mol Imaging. 2004;31:5–12
- . Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells. J Nucl Med. 2002;43:1210–1217
- Imaging proliferation in lung tumors with PET: 18F-FLT versus 18F-FDG. J Nucl Med. 2003;44:1426–1431
☆ This study was supported by a grant from the National R&D Program for Cancer Control, Ministry of Health, Welfare and Family affairs, Republic of Korea (0620220) and Nuclear R&D program through KOSEF (M20702000003-08N0200-00310).
PII: S0969-8051(09)00035-3
doi: 10.1016/j.nucmedbio.2009.01.010
© 2009 Elsevier Inc. All rights reserved.
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Nuclear Medicine and Biology
Volume 36, Issue 4
, Pages 427-433
, May 2009
