Nuclear Medicine and Biology
Volume 36, Issue 4 , Pages 411-417, May 2009

Validation of an 18F-labeled biphenylalkyne as a positron emission tomography imaging agent for β-amyloid plaques

  • Shiaw-Pyng Wey

      Affiliations

    • Department of Medical Imaging and Radiological Sciences, Graduate Institute of Medical Physics and Imaging Science, Chang Gung University, Taoyuan, 333 Taiwan
    • Molecular Imaging Center, Chang Gung Memorial Hospital, Taoyuan, 333 Taiwan
    • There authors contributed equally to this work.
  • ,
  • Chi-Chang Weng

      Affiliations

    • Department of Medical Imaging and Radiological Sciences, Graduate Institute of Medical Physics and Imaging Science, Chang Gung University, Taoyuan, 333 Taiwan
    • There authors contributed equally to this work.
  • ,
  • Kun-Ju Lin

      Affiliations

    • Department of Medical Imaging and Radiological Sciences, Graduate Institute of Medical Physics and Imaging Science, Chang Gung University, Taoyuan, 333 Taiwan
    • Molecular Imaging Center, Chang Gung Memorial Hospital, Taoyuan, 333 Taiwan
  • ,
  • Cheng-Hsiang Yao

      Affiliations

    • Molecular Imaging Center, Chang Gung Memorial Hospital, Taoyuan, 333 Taiwan
  • ,
  • Tzu-Chen Yen

      Affiliations

    • Department of Medical Imaging and Radiological Sciences, Graduate Institute of Medical Physics and Imaging Science, Chang Gung University, Taoyuan, 333 Taiwan
    • Molecular Imaging Center, Chang Gung Memorial Hospital, Taoyuan, 333 Taiwan
  • ,
  • Hank F. Kung

      Affiliations

    • Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
  • ,
  • Daniel Skovronsky

      Affiliations

    • Avid Radiopharmaceuticals Inc, Philadelphia, PA 19104, USA
  • ,
  • Mei-Ping Kung

      Affiliations

    • Department of Medical Imaging and Radiological Sciences, Graduate Institute of Medical Physics and Imaging Science, Chang Gung University, Taoyuan, 333 Taiwan
    • Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    • Corresponding Author InformationCorresponding author. Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA. Tel.: +1 215 662 3989; fax: +1 215 349 5035.

Received 9 December 2008; received in revised form 13 January 2009; accepted 23 January 2009. published online 31 March 2009.

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 This work was supported by a grant (no. 34004) from Chang Gung Medical Research Program.

PII: S0969-8051(09)00034-1

doi:10.1016/j.nucmedbio.2009.01.013

Nuclear Medicine and Biology
Volume 36, Issue 4 , Pages 411-417, May 2009