Nuclear Medicine and Biology
Volume 36, Issue 4 , Pages 395-402, May 2009

A simplified suite of methods to evaluate chelator conjugation of antibodies: effects on hydrodynamic radius and biodistribution

  • Fares Al-Ejeh

      Affiliations

    • Experimental Therapeutics Laboratory, Hanson Institute, Adelaide SA 5000, Australia
  • ,
  • Jocelyn M. Darby

      Affiliations

    • Experimental Therapeutics Laboratory, Hanson Institute, Adelaide SA 5000, Australia
  • ,
  • Benjamin Thierry

      Affiliations

    • Ian Wark Research Institute, University of South Australia, Adelaide SA 5000, Australia
  • ,
  • Michael P. Brown

      Affiliations

    • Experimental Therapeutics Laboratory, Hanson Institute, Adelaide SA 5000, Australia
    • Department of Medical Oncology, Royal Adelaide Hospital Cancer Centre, and School of Medicine, University of Adelaide, Adelaide SA 5000, Australia
    • Corresponding Author InformationCorresponding author. Department of Medical Oncology, Royal Adelaide Hospital, MDP 11, Level 4, East Wing, North Terrace, Adelaide SA 5000, Australia. Tel.: +61 8 8222 4398; fax: +61 8 8222 4358.

Received 13 November 2008; received in revised form 18 December 2008; accepted 13 January 2009. published online 31 March 2009.

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PII: S0969-8051(09)00008-0

doi:10.1016/j.nucmedbio.2009.01.001

Nuclear Medicine and Biology
Volume 36, Issue 4 , Pages 395-402, May 2009