« Previous
Next »
Nuclear Medicine and Biology
Volume 36, Issue 2
, Pages 129-135
, February 2009
Development of [90Y]DOTA-conjugated bisphosphonate for treatment of painful bone metastases
References
- . Breakthrough pain: characteristics and impact in patients with cancer pain. Pain. 1999;81:129–134
- . Management of cancer pain. Lancet. 1999;353:1695–1700
- . Malignant bone pain: pathophysiology and treatment. Pain. 1997;69:1–18
- . Radiation therapy in the management of symptomatic bone metastases: the effect of total dose and histology on pain relief and response duration. Int J Radiat Oncol Biol Phys. 1998;42:1119–1126
- . Bone-seeking radionuclides for therapy. J Nucl Med. 2005;46(Suppl 1):38S–47S
- . Yttrium-90–citrat zur schmerztherapie bei knochenmetastasen ([Yttrium–citrate for pain-therapy by bone metastases]), NUC Compact. 1990;21:128–132
- Radiation doses of yttrium-90 citrate and yttrium-90 EDTMP as determined via analogous yttrium-86 complexes and positron emission tomography. Eur J Nucl Med. 1996;23:958–966
- Design of a radiopharmaceutical for the palliation of painful bone metastases: rhenium-186-labeled bisphosphonate derivative. J Labelled Comp Radiopharm. 2004;47:753–761
- Development of a rhenium-186-labeled MAG3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals. Bioconjug Chem. 2005;16:751–757
- Rhemium-186-monoaminemonoamidedithiol-conjugated bisphosphonate derivatives for bone pain palliation. Nucl Med Biol. 2006;33:513–520
- Therapeutic effects of a 186Re-complex-conjugated bisphosphonate for the palliation of metastatic bone pain in an animal model. J Nucl Med. 2007;48:122–127
- Assessment of 186Re chelate-conjugated bisphosphonate for the development of new radiopharmaceuticals for bones. Nucl Med Biol. 2007;34:79–87
- Usefulness of competitive inhibitors of protein binding for improving the pharmacokinetics of 186Re-MAG3-conjugated bisphosphonate (186Re-MAG3-HBP), an agent for treatment of painful bone metastases. Eur J Nucl Med Mol Imaging. 2009;36:115–121
- Bone marrow absorbed dose of rhenium-186-HEDP and the relationship with decreased platelet counts. J Nucl Med. 1996;37:38–41
- . Dosimetry of 188Re-hydroxyethylidene diphosphonate in human prostate cancer skeletal metastases. J Nucl Med. 2003;44:953–960
- . OLINDA/EXM: the second-generation personal computer software for internal dose assessment in nuclear medicine. J Nucl Med. 2005;46:1023–1027
- Yttrium-90 and indium-111 labelling, receptor binding and biodistribution of [DOTA0,d-Phe1,Tyr3]octreotide, a promising somatostatin analogue for radionuclide therapy. Eur J Nucl Med. 1997;24:368–371
- Receptor-mediated radiotherapy with 90Y-DOTA-d-Phe1-Tyr3-octreotide. Eur J Nucl Med. 2001;28:426–434
- . Skeletal localization of samarium-153 chelates: potential therapeutic bone agents. J Nucl Med. 1987;28:495–504
- . ‘Magic bullets’ for bone diseases: progress in rational design of bone-seeking medicinal agents. Chem Soc Rev. 2007;36:507–531
- . Tc-EHDP: a potential radiopharmaceutical for skeletal imaging. J Nucl Med. 1972;13:947–950
- . Structural characterization of a technetium-99-diphosphonate complex. Implications for the chemistry of technetium-99m skeletal imaging agents. J Am Chem Soc. 1980;102:2476–2478
- . Determination of charge and size of technetium diphosphonate complexes by anion-exchange liquid chromatography. Anal Chem. 1985;57:246–253
- . The chemistry of rhenium and technetium as related to the use of isotopes of these elements in therapeutic and diagnostic nuclear medicine. Nucl Med Biol. 1986;13:465–477
- . Pharmacokinetics of rhenium-186 after administration of rhenium-186-HEDP to patients with bone metastases. J Nucl Med. 1992;33:646–651
- . Development of a novel 99mTc-chelate-conjugated bisphosphonate with high affinity for bone as a bone scintigraphic agent. J Nucl Med. 2006;47:2042–2047
- A new bisphosphonate-containing 99mTc(I) tricarbonyl complex potentially useful as bone-seeking agent: synthesis and biological evaluation. J Biol Inorg Chem. 2007;12:667–679
- Development of a conjugate of 99mTc-EC with aminomethylenediphosphonate in the search for a bone tracer with fast clearance from soft tissue. Bioconjug Chem. 2002;13:16–22
- A bisphosphonate monoamide analogue of DOTA: a potential agent for bone targeting. J Am Chem Soc. 2005;127:16477–16485
- . The influence of multidentate organic phosphonates on the crystal growth of hydroxyapatite. Calcif Tissue Res. 1973;13:295–303
- . Structural requirements for bisphosphonate actions in vitro. J Bone Miner Res. 1994;9:1875–1882
- . At- and 131I-labeled bisphosphonates with high in vivo stability and bone accumulation. J Nucl Med. 1999;40:1197–1203
- . Comparison of biological characteristics of EDTMP complexes with 99mTc, 111In and 153Sm in rats. Appl Radiat Isot. 1994;45:949–953
- . Sm-EDTMP and 186Re-HEDP as bone therapeutic radiopharmaceuticals. Int J Rad Appl Instrum B. 1987;14:223–232
- Lu-labeled cyclic polyaminophosphonates as potential agents for bone pain palliation. Appl Radiat Isot. 2002;57:177–184
PII: S0969-8051(08)00246-1
doi: 10.1016/j.nucmedbio.2008.11.007
© 2009 Elsevier Inc. All rights reserved.
« Previous
Next »
Nuclear Medicine and Biology
Volume 36, Issue 2
, Pages 129-135
, February 2009
