Nuclear Medicine and Biology
Volume 36, Issue 2 , Pages 171-181 , February 2009

In vitro and in vivo analysis of [64Cu-NO2A-8-Aoc-BBN(7–14)NH2]: a site-directed radiopharmaceutical for positron-emission tomography imaging of T-47D human breast cancer tumors

  • Adam F. Prasanphanich

      Affiliations

    • Department of Radiology, University of Missouri School of Medicine, Columbia, MO 65211, USA
    • Research Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201, USA
  • ,
  • Lauren Retzloff

      Affiliations

    • Department of Molecular Pharmacology and Physiology, University of Missouri School of Medicine, Columbia, MO 65211, USA
  • ,
  • Stephanie R. Lane

      Affiliations

    • Department of Chemistry, University of Missouri, Columbia, MO 65211, USA
  • ,
  • Prasant K. Nanda

      Affiliations

    • Department of Radiology, University of Missouri School of Medicine, Columbia, MO 65211, USA
  • ,
  • Gary L. Sieckman

      Affiliations

    • Research Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201, USA
  • ,
  • Tammy L. Rold

      Affiliations

    • The Radiopharmaceutical Sciences Institute, University of Missouri School of Medicine, Columbia, MO 65211, USA
    • Department of Internal Medicine, University of Missouri School of Medicine, Columbia, MO 65211, USA
  • ,
  • Lixin Ma

      Affiliations

    • Department of Radiology, University of Missouri School of Medicine, Columbia, MO 65211, USA
    • Research Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201, USA
    • The Radiopharmaceutical Sciences Institute, University of Missouri School of Medicine, Columbia, MO 65211, USA
    • International Institute of Nano and Molecular Medicine, University of Missouri School of Medicine, Columbia, MO 65211, USA
  • ,
  • Said D. Figueroa

      Affiliations

    • Department of Radiology, University of Missouri School of Medicine, Columbia, MO 65211, USA
    • Research Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201, USA
  • ,
  • Samantha V. Sublett

      Affiliations

    • The Radiopharmaceutical Sciences Institute, University of Missouri School of Medicine, Columbia, MO 65211, USA
  • ,
  • Timothy J. Hoffman

      Affiliations

    • Research Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201, USA
    • The Radiopharmaceutical Sciences Institute, University of Missouri School of Medicine, Columbia, MO 65211, USA
    • Department of Internal Medicine, University of Missouri School of Medicine, Columbia, MO 65211, USA
  • ,
  • Charles J. Smith

      Affiliations

    • Department of Radiology, University of Missouri School of Medicine, Columbia, MO 65211, USA
    • Research Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201, USA
    • Department of Molecular Pharmacology and Physiology, University of Missouri School of Medicine, Columbia, MO 65211, USA
    • The Radiopharmaceutical Sciences Institute, University of Missouri School of Medicine, Columbia, MO 65211, USA
    • University of Missouri Research Reactor Center, University of Missouri, Columbia, MO 65211, USA
    • Corresponding Author InformationCorresponding author. Harry S. Truman Memorial VA Hospital, Research Service Room A005, 800 Hospital Drive, Columbia, MO 65201, USA. Tel.: +1 573 814 6000x53683; fax: +1 573 882 1663.

Received 3 October 2008 ,Revised 4 November 2008 ,Accepted 11 November 2008.

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 This work was funded in part by The United States Department of Veterans' Affairs VA Merit Award.

PII: S0969-8051(08)00245-X

doi: 10.1016/j.nucmedbio.2008.11.005

Nuclear Medicine and Biology
Volume 36, Issue 2 , Pages 171-181 , February 2009