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Nuclear Medicine and Biology
Volume 36, Issue 2
, Pages 107-116
, February 2009
18F-Labeled benzylideneaniline derivatives as new ligands for β-amyloid plaque imaging in Alzheimer's disease
References
- . The cause of neuronal degeneration in Alzheimer's disease. Prog Neurobiol. 2000;60:139–165
- . Molecular genetics of familial Alzheimer disease. Am J Med Sci. 1998;315:266–272
- . Alzheimer's disease and Parkinson's disease. N Engl J Med. 2003;348:1356–1364
- . The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 2002;297:353–356
- . Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. Annu Rev Pharmacol Toxicol. 2003;43:545–584
- . Imaging is superior to cognitive testing for early diagnosis of Alzheimer's disease. Neurobiol Aging. 2004;25:685–691
- . Amyloid β-protein and the genetics of Alzheimer's disease. J Biol Chem. 1996;271:18295–18298
- . Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron. 1996;16:921–932
- . Detection of neuritic plaques in Alzheimer's disease by magnetic resonance microscopy. Proc Natl Acad Sci U S A. 1999;96:14079–14084
- Detection of amyloid plaques in mouse models of Alzheimer's disease by magnetic resonance imaging. Magn Reson Med. 2004;51:452–457
- . 19F and 1H MRI detection of amyloid β plaques in vivo. Nat Neurosci. 2005;8:527–533
- In vivo detection of amyloid-β deposits by near-infrared imaging using an oxazine-derivative probe. Nat Biotechnol. 2005;23:577–583
- Imaging of amyloid-β deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy. Nat Med. 2001;7:369–372
- . Development of an optical approach for noninvasive imaging of Alzheimer's disease pathology. J Biomed Opt. 2005;10:11007
- . PET imaging of amyloid in Alzheimer's disease. Lancet Neurol. 2004;3:519–527
- Neuroimaging of vessel amyloid in Alzheimer's disease. Ann N Y Acad Sci. 1997;826:242–247
- . Novel stilbenes as probes for amyloid plaques. J Am Chem Soc. 2001;123:12740–12741
- Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates. J Med Chem. 2001;44:1905–1914
- . X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology. J Histochem Cytochem. 2000;48:1223–1232
- Imaging Aβ plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. J Neuropathol Exp Neurol. 2002;61:797–805
- . Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents. J Med Chem. 2003;46:2740–2754
- . Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain. Life Sci. 2001;69:1471–1484
- IMPY: an improved thioflavin-T derivative for in vivo labeling of beta-amyloid plaques. Brain Res. 2002;956:202–210
- Synthesis and evaluation of benzothiophene derivatives as ligands for imaging β-amyloid plaques in Alzheimer's disease. Nucl Med Biol. 2006;33:811–820
- Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease. J Neurosci. 2001;21:RC189
- . Chemistry of fluorine-18 radiopharmaceuticals. Int J Rad Appl Instrum A. 1986;37:685–693
- . Comparison of the electronic structures of imine and hydrazone side-chain functionalities with the aid of 13C and 15N NMR chemical shifts and PM3 calculations. The influence of C
N-substitution on the sensitivity to aromatic substitution. J Org Chem. 2003;68:2151–2160 - Preparation of 18F-human serum albumin: a simple and efficient protein labeling method with 18F using a hydrazone-formation method. Bioconjug Chem. 2005;16:1329–1333
- . Substituent effects, electronic transmission, and structural dependence of pi delocalization as studied with the p-fluorophenyl tag. J Am Chem Soc. 1972;94:9113–9122
- . Hydrogenation of N-benzylideneaniline with CO+H2O and transalkylation reactions of benzaldehyde with tertiary aliphatic amines catalyzed by iron pentacarbonyl. J Mol Catalysis. 1983;22:195–203
- . Hydrogenation of N-benzylideneaniline with molecular hydrogen using iron pentacarbonyl as catalyst precursor. J Organometallic Chem. 1984;262:359–364
- . Synthesis, radiolabeling and tissue distribution of 11 beta-fluoroalkyl- and 11 beta-fluoroalkoxy-substituted estrogens: target tissue uptake selectivity and defluorination of a homologous series of fluorine-18-labeled estrogens. Nucl Med Biol. 1993;20:31–47
- . β-Amyloid imaging probes. Nucl Med Mol Imaging. 2007;41:112–117
- . Imaging amyloid-β deposits in vivo. J Cereb Blood Flow Metab. 2002;22:1035–1041
- Imaging of amyloid β in Alzheimer's disease with 18F-BAY94-9172, novel PET tracer: proof of mechanism. Lancet Neurol. 2008;7:129–135
PII: S0969-8051(08)00242-4
doi: 10.1016/j.nucmedbio.2008.11.004
© 2009 Elsevier Inc. All rights reserved.
« Previous
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Nuclear Medicine and Biology
Volume 36, Issue 2
, Pages 107-116
, February 2009
