Nuclear Medicine and Biology
Volume 36, Issue 1 , Pages 29-38, January 2009

5-[18F]Fluoroalkyl pyrimidine nucleosides: probes for positron emission tomography imaging of herpes simplex virus type 1 thymidine kinase gene expression

  • Ann-Marie Chacko

      Affiliations

    • Institute for Environmental Medicine, Targeted Therapeutics Program, University of Pennsylvania, Philadelphia, PA 19104, USA
  • ,
  • Eric Blankemeyer

      Affiliations

    • Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
  • ,
  • Brian P. Lieberman

      Affiliations

    • Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
  • ,
  • Wenchao Qu

      Affiliations

    • Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
  • ,
  • Hank F. Kung

      Affiliations

    • Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    • Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA
    • Corresponding Author InformationCorresponding author. Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA. Tel.: +1 215 662 3096; fax: +1 215 349 5035.

Received 25 September 2008; accepted 10 October 2008.

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 This work was supported by a grant awarded from the National Institutes of Health (R21-EB-005242) to H.F.K. A travel award to A.-M.C. from the Educational Research Fund of the Society of Nuclear Medicine (SNM) supported the presentation of the preliminary results at the 2008 SNM Annual Meeting in New Orleans, LA.

PII: S0969-8051(08)00204-7

doi:10.1016/j.nucmedbio.2008.10.009

Nuclear Medicine and Biology
Volume 36, Issue 1 , Pages 29-38, January 2009