Nuclear Medicine and Biology
Volume 35, Issue 8 , Pages 869-874, November 2008

Peripheral metabolism of [18F]FDDNP and cerebral uptake of its labelled metabolites

  • Gert Luurtsema

      Affiliations

    • Department of Nuclear Medicine and PET Research, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 0 20 4443999.
  • ,
  • Robert C. Schuit

      Affiliations

    • Department of Nuclear Medicine and PET Research, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
  • ,
  • Kevin Takkenkamp

      Affiliations

    • Department of Nuclear Medicine and PET Research, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
  • ,
  • Mark Lubberink

      Affiliations

    • Department of Nuclear Medicine and PET Research, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
  • ,
  • N. Harry Hendrikse

      Affiliations

    • Clinical Pharmacology and Pharmacy, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
  • ,
  • Albert D. Windhorst

      Affiliations

    • Department of Nuclear Medicine and PET Research, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
  • ,
  • Carla F.M. Molthoff

      Affiliations

    • Department of Nuclear Medicine and PET Research, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
  • ,
  • Nelleke Tolboom

      Affiliations

    • Alzheimer Centre and Department of Neurology, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
  • ,
  • Bart N.M. van Berckel

      Affiliations

    • Department of Nuclear Medicine and PET Research, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands
  • ,
  • Adriaan A. Lammertsma

      Affiliations

    • Department of Nuclear Medicine and PET Research, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands

Received 20 June 2008; received in revised form 11 August 2008; accepted 5 September 2008.

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 This work was funded in part by the EU FP6 project DiMI, LSHB-CT-2005-512146.

PII: S0969-8051(08)00181-9

doi:10.1016/j.nucmedbio.2008.09.002

Nuclear Medicine and Biology
Volume 35, Issue 8 , Pages 869-874, November 2008