Nuclear Medicine and Biology
Volume 35, Issue 6 , Pages 645-653, August 2008

The level of insulin growth factor-1 receptor expression is directly correlated with the tumor uptake of 111In-IGF-1(E3R) in vivo and the clonogenic survival of breast cancer cells exposed in vitro to trastuzumab (Herceptin)☆

  • Bart Cornelissen

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • ,
  • Kristin McLarty

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • ,
  • Veerle Kersemans

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • ,
  • Raymond M. Reilly

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada M5S 3M2
    • Department of Medical Imaging, University of Toronto, Toronto, ON, Canada M5S 3M2
    • Toronto General Research Institute, University Health Network Toronto, Toronto, ON, Canada M5S 3M2
    • Corresponding Author InformationCorresponding author. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada M5S 3M2. Tel.: +1 416 946 5522; fax: +1 416 978 8511.

Received 9 April 2008; received in revised form 24 May 2008; accepted 27 May 2008.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

☆ This study was supported by grants from the Ontario Cancer Research Network (No. 03-NOV-0428; One Millimetre Cancer Challenge Imaging Platform) with funds from the Province of Ontario. Kristin McLarty was supported by a Canadian Institutes of Health Research (CIHR) Excellence in Radiation Research (EIRR) fellowship. Veerle Kersemans was supported by a Wyeth-CIHR postdoctoral fellowship.

PII: S0969-8051(08)00118-2

doi:10.1016/j.nucmedbio.2008.05.010

Nuclear Medicine and Biology
Volume 35, Issue 6 , Pages 645-653, August 2008

Article Tools

* Image Usage & Resolution