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Nuclear Medicine and Biology
Volume 35, Issue 6
, Pages 679-687
, August 2008
Radiolabeling of annexin A5 with 99mTc: comparison of HYNIC-Tc vs. iminothiolane-Tc-tricarbonyl conjugates
References
- . The annexins. Genome Biol. 2004;5:219
- Past, present and future of annexin V: from protein discovery to clinical applications. J Nucl Med. 2005;46:2035–2050
- Annexin A5 scintigraphy of forearm as a novel in vivo model of skeletal muscle preconditioning in humans. Circulation. 2005;111:173–178
- . Sequential 99mTc-hydrazinonicotinamide-annexin V imaging for predicting response to chemotherapy. J Nucl Med. 2006;47:1813–1818
- Mapping of treatment-induced apoptosis in normal structures: 99mTc-HYNIC-rh-annexin V SPECT and CT image fusion. Eur J Nucl Med Mol Imaging. 2006;33(8):893–899
- . Annexin V SPECT imaging phosphatidylserine expression in patients with dementia. Neurology. 2006;66:1253–1254
- . Prognostic significance of 99mTc HYNIC-rh-annexin V scintigraphy during platinum-based chemotherapy in advanced lung cancer. J Clin Oncol. 2007;25(18):2534–2539
- Noninvasive detection of programmed cell loss with 99mTc-labeled annexin A5 in heart failure. J Nucl Med. 2007;48(4):562–567
- Prediction of antitumor necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease. Gut. 2007;56(4):509–517
- . Tc-99m direct labeling of annexin V for potential apoptosis imaging in vivo [abstract]. J Label Compd Radiopharm. 2003;46(Suppl 1):S324
- In vivo detection and imaging of phosphatidylserine expression during programmed cell death. Proc Natl Acad Sci. 1998;95:6349–6354
- Visualisation of cell death in vivo in patients with acute myocardial infarction. Lancet. 2000;256:209–212
- Development and biologic evaluation of a kit for preformed chelate technetium-99m radiolabeling of an antibody Fab fragment using a diamide dimercaptide chelating agent. J Nucl Med. 1991;32:1445–1451
- . In vivo and in vitro measurement of apoptosis in breast cancer cells using 99mTc-EC-annexin V. Cancer Biother Radiopharm. 2001;16:73–83
- . A simplified method for preparation of 99mTc-annexin V and its biologic evaluation for in vivo imaging of apoptosis after photodynamic therapy. J Nucl Med. 2003;44:650–656
- . Evaluation of 99mTc-MAG3-annexin V: influence of the chelate on in vitro and in vivo properties in mice. Nucl Med Biol. 2006;33:135–144
- . 94mTc and 64Cu labeled annexin V positron emitting radiopharmaceuticals to study apoptosis [abstract]. J Label Compd Radiopharm. 2003;46(Suppl 1):S335
- Labeling annexin V with 99mTc-tricarbonyl PADA improved its organ clearance property [abstract]. J Nucl Med. 2002;43(5):374P
- . 99mTc (+I) tricarbonyl labeled hynic-annexin V as a potential apoptosis imaging agent [abstract]. J Nucl Med. 2003;44(5):316P
- Iodination of annexin V for imaging apoptosis. J Nucl Med. 2002;43:671–677
- . Synthesis and evaluation of a 18F-labelled recombinant annexin V derivative, for identification and quantification of apoptotic cells with PET. Appl Radiat Isotopes. 2003;58:201–207
- . `Apoptosis induced by drug treatment correlates with uptake of 111In labelled pegylated annexin V in MDA-MB468 tumors. J Nucl Med. 2002;43:41
- . Development of a new ligand, 11C-labeled annexin V, for PET imaging of apoptosis [abstract]. J Nucl Med. 2002;43(5):362P
- . 68Ga Labelling of annexin V: comparison to 99mTc-annexin V and 67Ga annexin [abstract]. J Nucl Med. 2003;44(5):49P–50P
- . Development and characterization of annexin V mutants with endogenous chelation sites for 99mTc. Bioconjug Chem. 2000;11:918–925
- . Development of annexin V mutants suitable for labeling with Tc(I)-carbonyl complex. Bioconjug Chem. 2002;13:1119–1123
- 99mTc-Labeled annexin V fragments: a potential SPECT radiopharmaceutical for imaging cell death. Nucl Med Biol. 2006;33:635–643
- Radiosynthesis of a [18F]fluoropyridine-based maleimide reagent for protein labelling [abstract]. J Label Compd Radiopharm. 2003;46:S15
- . A new 18F and 99mTc radiopeptides for apoptosis imaging in tumor bearing mice [abstract]. J Nucl Med. 2003;44(5):49P
- Imaging of apoptosis (programmed cell death) with 99mTc annexin V. J Nucl Med. 1999;40:184–191
- . A novel ternary ligand system for 99mTc-labelling of hydrazinonicotinamide-modified biologically active molecules using imine-N-containing heterocycles as coligands. Bioconjug Chem. 1998;9:583–595
- . New and versatile ternary ligand system for technetium radiopharmaceuticals: water soluble phosphines and tricine coligands in labeling hydrazinonicotinamide-modified cyclic glycoprotein IIb/IIIa antagonist with 99mTc. Biochem Chem. 1997;8:146–154
- 99mTc-HYNIC-derivatized ternary ligand complexes for 99mTc-labeled polypeptides with low in vivo protein binding. Nucl Med Biol. 2001;28:215–224
- . In vitro cell studies of technetium-99m labeled RGD-HYNIC peptide, a comparison of tricine and EDDA as co-ligands. Nucl Med Biol. 2003;30:141–149
- . Direct labeling of proteins with 99mTc. Nucl Med Biol. 1991;18(7):667–676
- Labeling a hydrazinonicotinamide-modified cyclic IIb/IIIa receptor antagonist with 99mTc using aminocarboxylates as coligands. Bioconjugate Chem. 1996;7:63–71
- Nitriles form mixed-coligand complexes with 99mTc-HYNIC-peptide. Nucl Med Biol. 2001;29:107–113
- . Radiomarquage des macromolécules par le technétium-99m - voie indirecte. In: Comet M, Vidal M editor. Radiopharmaceutiques. Grenoble: Presses Universitaires de Grenoble; 1998;p. 379–395
- . New directions in the coordination chemistry of 99mTc: a reflection on technetium core structures and strategy for new chelate design. Nucl Med Biol. 2005;32:1–20
- Tumor imaging with technetium 99m-labeled hydrazinonicotinamide-Fab' conjugates. J Nucl Med. 1997;38:133–138
- In vivo and in vitro characterization of three 99mTc-labeled monoclonal antibody G250 preparation. J Nucl Med. 1999;40:829–836
- Plasma protein binding of 99mTc-labeled hydrazino nicotinamide derivatized polypeptides and peptides. Nucl Med Biol. 2001;28:155–164
- . A comparison in monkeys of 99mTc labeled to a peptide by 4 methods. J Nucl Med. 2001;42:1870–1877
- . Improved detection of cell death in vivo with annexin V radiolabeled by site-specific method. J Nucl Med. 2006;47(9):1546–1553
- Intracellular metabolic fate of radioactivity after injection of technetium 99m-labeled hydrazino nicotinamide derivatized proteins. Bioconjug Chem. 1999;10:386–394
- . Improvement of radiolabelling proteins with the 99mTc-tricarbonyl-core [99mTc(CO)3]+, by thiol-derivatization with iminothiolane: application to γ-globulins and annexin V. J Label Compd Radiopharm. 2005;48:873–885
- Organometallic 99mTc-aquaion labels peptide to an unprecedented high specific activity. J Nucl Med. 1999;40:1913–1917
- Technetium-99m-human polyclonal IgG radiolabeled via hydrazinonicotinamide derivative for imaging focal sites of injection in rats. J Nucl Med. 1990;31:2022–2027
- . Simplified method for conjugating macrocyclic bifunctional chelating agents to antibodies via 2-iminothiolane. Bioconjug Chem. 1990;1:222–226
- . Synthesis and preliminary evaluation of Tc-99m-labeled somatostatin analog (RC-160) using «3 + 1» mixed ligand approach. Nucl Med Biol. 2000;28:225–233
- . Preparation of protein conjugates via intermolecular hydrazone linkage. Biochemistry. 1986;25:5574–5579
- . Radiomarquage des anticorps monoclonaux et des peptides par le technétium 99m – voie directe. In: Comet M, Vidal M editor. Radiopharmaceutiques. Grenoble: Presses Universitaires de Grenoble; 1998;p. 365–378
- . Stratégies de marquage d'anticorps monoclonaux et molécules apparentées par le technétium-99m. J Med Nucl Biophys. 1991;4:401–409
- . Measurement of the affinity and cooperativity of annexin V-membrane binding under conditions of low membrane occupancy. Anal Biochem. 2004;329:112–119
- . Increased erythrocyte phosphatidylserine exposure in sickle cell disease: flow-cytometric measurement and clinical association. Blood. 1996;88(5):1873–1880
- . Primary structure of human placental anticoagulant protein. Biochemistry. 1987;26:8087–8092
- Trans- and cis-water reactivities in d6 octahedral ruthenium(+II) pentaaqua complexes: experimental and density functional theory studies. Inorganic Chem. 1997;36:6009–6020
- . Potential of the “[M(CO)3]+” (M=Re, Tc) moiety for the labeling of biomolecules. Radiochim Acta. 1997;79:99–103
- Stable one-step technetium 99m labeling of His-tagged recombinant proteins with a novel Tc(+I)-carbonyl complex. Nat Biotechnol. 1999;17:897–901
- . Thiol- and thioether-based bifunctional chelates for the {M(CO)3}+ core (M=Tc, Re). Inorg Chem. 2005;44:6763–6770
- . Spectrophotometric assay of thiols. Methods Enzymol. 1987;143:44–67
- . Reactions with the technetium and rhenium carbonyl complexes (NEt4)[MX3(CO)3]. Synthesis and structure of Tc(CN-But)3(CO)3](NO3) and (NEt4)[Tc2(μ-SCH2CH2OH)3(CO)3]. Polyhedron. 1996;15:1079–1089
- . N-(2-Mercaptoethyl)picolylamine as a diaminomonothiolate ligand for the “fac-[Re(CO)3]+” core. Inorg Chem. 2002;41:6181–6183
- Influence of the density of ligand systems on the in vitro and in vivo behavior of 99mTc-tricarbonyl complexes: a hint for the future functionalization of biomolecules. Bioconjug Chem. 2000;11:345–351
- . A new [2+1] mixed ligand concept based on [99(m)Tc(OH2)3(CO)3]+: a basic study. Dalton Trans. 2004;1320–1328
PII: S0969-8051(08)00117-0
doi: 10.1016/j.nucmedbio.2008.05.009
© 2008 Elsevier Inc. All rights reserved.
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Nuclear Medicine and Biology
Volume 35, Issue 6
, Pages 679-687
, August 2008
