Nuclear Medicine and Biology
Volume 35, Issue 6 , Pages 655-663, August 2008

Evaluation of a bromine-76-labeled progestin 16α,17α-dioxolane for breast tumor imaging and radiotherapy: in vivo biodistribution and metabolic stability studies

  • Dong Zhou

      Affiliations

    • Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
  • ,
  • Terry L. Sharp

      Affiliations

    • Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
  • ,
  • Nicole M. Fettig

      Affiliations

    • Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
  • ,
  • Hsiaoju Lee

      Affiliations

    • Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
  • ,
  • Jason S. Lewis

      Affiliations

    • Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
  • ,
  • John A. Katzenellenbogen

      Affiliations

    • Department of Chemistry, University of Illinois, Urbana, IL 61801, USA
  • ,
  • Michael J. Welch

      Affiliations

    • Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA
    • Corresponding Author InformationCorresponding author. Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA. Tel.: +1 314 362 8436; fax: +1 314 362 8399.

Received 25 February 2008; accepted 2 May 2008. published online 01 July 2008.

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 This work was supported by the DOE (DE FG02 86ER60401 to JAK and DE FG02-84ER-60218 to MJW) and the NIH (PHS 2R01 CA25836 to JAK).

PII: S0969-8051(08)00108-X

doi:10.1016/j.nucmedbio.2008.05.001

Nuclear Medicine and Biology
Volume 35, Issue 6 , Pages 655-663, August 2008