Nuclear Medicine and Biology
Volume 35, Issue 3 , Pages 315-325 , April 2008

A novel radioligand for glycine transporter 1: characterization and use in autoradiographic and in vivo brain occupancy studies

  • Zhizhen Zeng

      Affiliations

    • Imaging, Merck Research Laboratories, West Point, PA 19486, USA
    • Corresponding Author InformationCorresponding author. Imaging, WP44C-2, Merck Research Laboratories, West Point, PA 19486, USA. Tel.: +1 215 652 5627; fax: +1 215 993 6803.
    • ,
  • Julie A. O'Brien

      Affiliations

    • Sleep and Psychiatric Disorders, Merck Research Laboratories, West Point, PA 19486, USA
    • ,
  • Wei Lemaire

      Affiliations

    • Medicinal Chemistry, Merck Research Laboratories, West Point, PA 19486, USA
    • ,
  • Stacey S. O'Malley

      Affiliations

    • Imaging, Merck Research Laboratories, West Point, PA 19486, USA
    • ,
  • Patricia J. Miller

      Affiliations

    • Imaging, Merck Research Laboratories, West Point, PA 19486, USA
    • ,
  • Zhijian Zhao

      Affiliations

    • Medicinal Chemistry, Merck Research Laboratories, West Point, PA 19486, USA
    • ,
  • Michael A. Wallace

      Affiliations

    • Drug Metabolism, Merck Research Laboratories, Rahway, NJ 07065, USA
    • ,
  • Conrad Raab

      Affiliations

    • Drug Metabolism, Merck Research Laboratories, West Point, PA 19486, USA
    • ,
  • Craig W. Lindsley

      Affiliations

    • Medicinal Chemistry, Merck Research Laboratories, West Point, PA 19486, USA
    • Departments of Pharmacology and Chemistry, Vanderbilt University, Nashville, TN 37232, USA
    • ,
  • Cyrille Sur

      Affiliations

    • Imaging, Merck Research Laboratories, West Point, PA 19486, USA
    • ,
  • David L. Williams Jr.

      Affiliations

    • Imaging, Merck Research Laboratories, West Point, PA 19486, USA

Received 10 September 2007 ,Revised 24 October 2007 ,Accepted 5 December 2007.

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PII: S0969-8051(07)00305-8

doi: 10.1016/j.nucmedbio.2007.12.002

Nuclear Medicine and Biology
Volume 35, Issue 3 , Pages 315-325 , April 2008

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