Nuclear Medicine and Biology
Volume 35, Issue 1 , Pages 11-17, January 2008

Dopamine D2 receptor radiotracers [11C](+)-PHNO and [3H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo

  • Patrick N. McCormick

      Affiliations

    • Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada M5S 1A8
    • Corresponding Author InformationCorresponding author. Tel.: +1 416 535 8501x4852; fax: +1 416 979 4656.
  • ,
  • Shitij Kapur

      Affiliations

    • Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada M5S 1A8
    • PET Center, Center for Addiction and Mental Health, Toronto, Ontario, Canada M5T 1R8
  • ,
  • Philip Seeman

      Affiliations

    • Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada M5S 1A8
    • Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 1A8
  • ,
  • Alan A. Wilson

      Affiliations

    • Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada M5S 1A8
    • PET Center, Center for Addiction and Mental Health, Toronto, Ontario, Canada M5T 1R8

Received 7 March 2007; received in revised form 17 August 2007; accepted 17 August 2007. published online 15 November 2007.

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PII: S0969-8051(07)00222-3

doi:10.1016/j.nucmedbio.2007.08.005

Nuclear Medicine and Biology
Volume 35, Issue 1 , Pages 11-17, January 2008