Nuclear Medicine and Biology
Volume 34, Issue 8 , Pages 887-896, November 2007

Effect of the EGFR density of breast cancer cells on nuclear importation, in vitro cytotoxicity, and tumor and normal-tissue uptake of [111In]DTPA-hEGF

Part of this work was presented at the Canadian Breast Cancer Research Alliance Reasons for Hope Conference, Montreal, Quebec, May 6–8, 2006.

  • Meiduo Hu

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada M5S 3M2
  • ,
  • Deborah Scollard

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada M5S 3M2
  • ,
  • Conrad Chan

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada M5S 3M2
  • ,
  • Paul Chen

      Affiliations

    • Neopharm, Inc., Waukegan, MI 60085-8328, USA
  • ,
  • Katherine Vallis

      Affiliations

    • Radiobiology Research Institute, University of Oxford, Oxford OX3 7LJ, UK
  • ,
  • Raymond M. Reilly

      Affiliations

    • Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada M5S 3M2
    • Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada M5G 1X5
    • Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada M5G 2C4
    • Corresponding Author InformationCorresponding author. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada M5S 3M2. Tel.: +1 416 946 5522; fax: +1 416 978 8511.

Received 27 April 2007; received in revised form 15 June 2007; accepted 25 June 2007. published online 03 September 2007.

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PII: S0969-8051(07)00175-8

doi:10.1016/j.nucmedbio.2007.06.010

Nuclear Medicine and Biology
Volume 34, Issue 8 , Pages 887-896, November 2007