Nuclear Medicine and Biology
Volume 34, Issue 5 , Pages 541-551, July 2007

Synthesis and positron emission tomography studies of C-11-labeled isotopomers and metabolites of GTS-21, a partial α7 nicotinic cholinergic agonist drug

  • Sung Won Kim

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • Department of Chemistry, State University of New York at Stony Brook, Stony Brook, NY 11794-3400, USA
    • Corresponding Author InformationCorresponding author. Department of Chemistry, State University of New York at Stony Brook, Stony Brook, NY 11794-3400, USA. Tel.: +1 631 344 4393; fax: +1 631 344 5815.
    • ,
  • Yu-Shin Ding

      Affiliations

    • Department of Chemistry, State University of New York at Stony Brook, Stony Brook, NY 11794-3400, USA
    • Department of Radiology, Yale University School of Medicine, New Haven, CT 06520-8048, USA
    • ,
  • David Alexoff

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • ,
  • Vinal Patel

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • ,
  • Jean Logan

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • ,
  • Kuo-Shyan Lin

      Affiliations

    • Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    • ,
  • Colleen Shea

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • ,
  • Lisa Muench

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • ,
  • Youwen Xu

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • ,
  • Pauline Carter

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • ,
  • Payton King

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • ,
  • Jasmine R. Constanzo

      Affiliations

    • Department of Chemistry, Fordham University, Bronx, NY 10458, USA
    • ,
  • James A. Ciaccio

      Affiliations

    • Department of Chemistry, Fordham University, Bronx, NY 10458, USA
    • ,
  • Joanna S. Fowler

      Affiliations

    • Medical Department, Brookhaven National Laboratory, Upton, NY 11973, USA
    • Department of Chemistry, State University of New York at Stony Brook, Stony Brook, NY 11794-3400, USA
    • Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA

Received 12 February 2007; received in revised form 2 April 2007; accepted 10 April 2007.

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PII: S0969-8051(07)00101-1

doi:10.1016/j.nucmedbio.2007.04.005

Nuclear Medicine and Biology
Volume 34, Issue 5 , Pages 541-551, July 2007

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