« Previous
Next »
Nuclear Medicine and Biology
Volume 34, Issue 5
, Pages 493-502
, July 2007
Preparation and biological evaluation of 111In-, 177Lu- and 90Y-labeled DOTA analogues conjugated to B72.3
References
- . Capromab pendetide: a review of its use as an imaging agent in prostate cancer. Drugs & Aging. 1998;12(4):293–304
- . Clinical role of indium-111 antimyosin imaging. Eur J Nucl Med. 1991;18(11):889–895
- Indium-111 OncoScint CR/OV and F-18 FDG in colorectal and ovarian carcinoma recurrences. Early observations. Clin Nucl Med. 1995;20(3):230–236
- 99mTc anti-CD15 monoclonal antibody (LeuTech) imaging improves diagnostic accuracy and clinical management in patients with equivocal presentation of appendicitis. Ann Surg. 2002;235(2):232–239
- . Cancer imaging with radiolabeled antibodies: new advances with technetium-99m-labeled monoclonal antibody Fab' fragments, especially CEA-scan and prospects for therapy. J Nucl Med Technol. 1997;25(1):18–23
- . Use of 90Y-ibritumomab tiuxetan in non-Hodgkin's lymphoma. Semin Oncol. 2005;32:S36–S43
- . Development of 131I-tositumomab. Semin Oncol. 2005;32:S50–S56
- . Radiometal-labeled agents (non-technetium) for diagnostic imaging. Chem Rev. 1999;99:2219–2234
- . 99mTc-Labeled Small Peptides as Diagnostic Radiopharmaceuticals. Chem Rev. 1999;99:2235–2268
- . Therapeutic radiopharmaceuticals. Chem Rev. 1999;99:2269–2292
- . Chelating agents for the binding of metal ions to macro molecules. Nature. 1974;250:587–588
- . A facile, water-soluble method for modification of proteins with DOTA. Use of elevated temperature and optimized pH to achieve high specific activity and high chelate stability in radiolabeled immunoconjugates. Bioconjug Chem. 1994;5:565–576
- . An improved method for conjugating monoclonal antibodies with N-hydroxysulfosuccinimidyl DOTA. Bioconjug Chem. 2001;12:320–324
- . Current and potential therapeutic uses of lanthanide radioisotopes. Cancer Biother Radiopharm. 2000;15:531–545
- . Bifunctional chelators for therapeutic lanthanide radiopharmaceuticals. Bioconjug Chem. 2001;12:7–34
- Synthesis, characterization, and 1/T1 NMRD profiles of gadolinium(III) complexes of monoamide derivatives of DOTA-like Ligands. X-ray Structure of 10-[2-[[2-Hydroxy-1-(hydroxymethyl)ethyl]amino]-1-[(phenylmethoxy)methyl]-2-oxo-ethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triaacetic acid-gadolinium(III) complex. Inorg Chem. 1992;31:2422–2428
- . Restoration of catalytic activity by replacement of a coordinated amide group: synthesis and laser-induced luminescence studies of the phosphate diester transesterification catalyst [Eu(NBAC)]3+. Inorg Chem. 1996;35:7466–7467
- . {DOTA-bis(amide)}lanthanide complexes: NMR evidence for differences in water-molecule exchange rates for coordination isomers. Chem Eur J. 2001;7:288–296
- . Unusually sharp dependence of water exchange rate versus lanthanide ionic radii for a series of tetraamide complexes. J Am Chem Soc. 2002;124:4226–4227
- . Steric control of lanthanide hydration state: fast water exchange at gadolinium in a mono-amide ‘DOTA’ complex. Dalton Trans. 2004;1441–1445
- . Modulation of the lifetime of water bound to lanthanide metal ions in complexes with ligands derived from 1,4,7,10-tetraazacyclododecane tetraacetate (DOTA). Helv Chim Acta. 2005;88:923–935
- . Structural characterization of a diprotonated ligand lanthanide complex — a key intermediate in lanthanide ion association and complex dissociation pathways. Dalton Trans. 2006;3291–3293
- In vivo comparison of macrocyclic and acyclic ligands for radiolabeling of monoclonal antibodies with 177Lu for radioimmunotherapeutic applications. Nucl Med Biol. 2002;29:431–442
- . Synthesis and biological evaluation of novel macrocyclic ligands with pendent donor groups as potential yttrium chelators for radioimmunotherapy with improved complex formation kinetics. J Med Chem. 2002;45:3458–3464
- . Radioactive metals in imaging and therapy. In: Meyer TJ editors. Comprehensive coordination chemistry II. vol. 9:London: Elsevier Ltd; 2004;p. 883–911
- Synthesis and evaluation of novel bifunctional chelating agents based on 1,4,7,10-tetraazacyclododecane-N,N′,Nʺ,Nʺ′-tetraacetic acid for radiolabeling proteins. Nucl Med Biol. 2003;30:581–595
- Radiolanthanide-labeled monoclonal antibody CC49 for radioimmunotherapy of cancer: biological comparison of DOTA conjugates and 149Pm, 166Ho and 177Lu. Bioconjug Chem. 2006;17:485–492
- Structure and solution stability of indium and gallium complexes of 1,4,7-triazacyclononanetriacetate and of ytrrium complexes of 1,4,7,10-tetraazacyclododecanetetraacetate and related ligands: kinetically stable complexes for use in imaging and radioimmunotherapy. X-ray molecular structure of the indium and gallium complexes of 1,4,7-triazacyclononane-1,4,7-triacetic acid. J Chem Soc Perkin Trans. 1991;2:87–99
- . Kinetics of formation and dissociation of lanthanide(III)–DOTA complexes. Inorg Chem. 1994;33:4070–4076
- . Complexing mechanism of the lanthanide cations Eu3+, Gd3+, and Tb3+ with 1,4,7,10-tetrakis(carboxymethyl)-1,4,7,10-tetraazacyclododecane (DOTA) — characterization of three successive complexing phases: study of the thermodynamic and structural properties of the complexes by potentiometry. Luminescence spectroscopy, and EXAFS. Chem Eur J. 2004;10:5218–5232
- . In vivo and In vitro clinical applications of monoclonal antibodies against TAG-72. Nucl Med Biol. 1991;18(4):395–401
- Tumor targeting with monoclonal antibody B72.3. Nucl Med Biol. 1989;16(2):137–142
- Development of an in vitro model for assessing the in vivo stability of lanthanide chelates. Nucl Med Biol. 2001;28:145–154
- . Evaluation of 177Lu-DOTA-labeled aglycosylated monoclonal anti-L1-CAM antibody chCE7: influence of the number of chelators on the in vitro and in vivo properties. Nucl Med Biol. 2006;33:883–889
- . In vitro and in vivo characterization of 64Cu-labeled abegrin, a humanized monoclonal antibody against integrin αVβ3. Cancer Res. 2006;66:9673–9681
- David Colcher, personal communication: “Unless there is evidence of aggregation, there is no alteration of RES uptake or metabolism of B72.3 as a function of chelates per antibody.”
- Comparative biodistributions of indium-111-labeled macrocycle chimeric B72.3 antibody conjugates in tumour-bearing mice. Br J Cancer. 1994;70:35–41
- . 90Y-DOTA-hLL2: an agent for radioimmunotherapy of non-Hodgkin's lymphoma. J Nucl Med. 2003;44:77–84
- . Dual isotope study of iodine-125 and indium-111-labeled antibody in athymic mice. J Nucl Med. 1989;30(3):374–384
- . Synthesis and X-ray structural characterization of seven co-ordinate macrocyclic In3+ complexes with relevance to radiopharmaceutical applications. J Chem Soc Chem Commun. 1989;460–462
PII: S0969-8051(07)00090-X
doi: 10.1016/j.nucmedbio.2007.03.006
© 2007 Elsevier Inc. All rights reserved.
« Previous
Next »
Nuclear Medicine and Biology
Volume 34, Issue 5
, Pages 493-502
, July 2007
