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Nuclear Medicine and Biology
Volume 34, Issue 4
, Pages 363-370
, May 2007
Radiolabeled high affinity peptidomimetic antagonist selectively targets αvβ3 receptor-positive tumor in mice
References
- . Integrin activation and structural rearrangement. Immunol Rev. 2002;186:141–163
- . Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med. 1995;1(1):27–31
- . Integrins, angiogenesis and vascular cell survival. Chem Biol. 1996;3(11):881–885
- . Arg-Gly-Asp: a versatile cell recognition signal. Cell. 1986;44(4):517–518
- . Alpha v integrins as receptors for tumor targeting by circulating ligands. Nat Biotechnol. 1997;15(6):542–546
- Radiolabeled αvβ3 integrin antagonists: a new class of tracers for tumor targeting. J Nucl Med. 1999;40(6):1061–1071
- Evaluation of a radiolabelled cyclic DTPA-RGD analogue for tumour imaging and radionuclide therapy. Int J Cancer. 2000;90(4):186–198
- Design, synthesis, and evaluation of radiolabeled integrin αvβ3 receptor antagonists for tumor imaging and radiotherapy. Cancer Biother Radiopharm. 2003;18(4):627–641
- . MicroPET and autoradiographic imaging of breast cancer αv-integrin expression using 18F- and 64Cu-labeled RGD peptide. Bioconjug Chem. 2004;15(1):41–49
- . Synthesis and biological evaluation of a 99mTc-labelled cyclic RGD peptide for imaging the αvβ3 expression. Nuklearmedizin. 2004;43(1):26–32
- Neovascular targeting with cyclic RGD peptide (cRGDf-ACHA) to enhance delivery of radioimmunotherapy. Cancer Biother Radiopharm. 2000;15(1):71–79
- Radiolabeled RGD-DTPA-Tyr3-octreotate for receptor-targeted radionuclide therapy. Cancer Biother Radiopharm. 2004;19(2):173–180
- . Increased cell death after therapy with an Arg-Gly-Asp-linked somatostatin analog. J Nucl Med. 2004;45(10):1716–1720
- Improved tumor targeting of radiolabeled RGD peptides using rapid dose fractionation. Cancer Biother Radiopharm. 2004;19(4):399–404
- 90Y and 111In complexes of a DOTA-conjugated integrin αvβ3 receptor antagonist: different but biologically equivalent. Bioconjug Chem. 2004;15(2):235–241
- Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001;42(2):326–336
- . Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation. Nucl Med Biol. 2004;31(1):11–19
- MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide. Eur J Nucl Med Mol Imaging. 2004;31(8):1081–1089
- Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor αvβ3-integrin expression. J Nucl Med. 2004;45(10):1776–1783
- MicroPET imaging of breast cancer αv-integrin expression with 64Cu-labeled dimeric RGD peptides. Mol Imaging Biol. 2004;6(5):350–359
- Integrin αvβ3-targeted imaging of lung cancer. Neoplasia. 2005;7(3):271–279
- MicroPET imaging of glioma integrin αvβ3 expression using 64Cu-labeled tetrameric RGD peptide. J Nucl Med. 2005;46(10):1707–1718
- Tumor regression by targeted gene delivery to the neovasculature. Science. 2002;296(5577):2404–2407
- A novel antiangiogenesis therapy using an integrin antagonist or anti-Flk-1 antibody coated 90Y-labeled nanoparticles. Int J Radiat Oncol Biol Phys. 2004;58(4):1215–1227
- Synthesis, in vitro, and in vivo characterization of an integrin αvβ3-targeted molecular probe for optical imaging of tumor. Bioorg Med Chem. 2005;13(11):3763–3771
- . Studies on renal tubular protein reabsorption: partial and near complete inhibition by certain amino acids. Scand J Clin Lab Invest. 1977;37(6):477–486
- Reduction of the renal uptake of radiolabeled monoclonal antibody fragments by cationic amino acids and their derivatives. Cancer Res. 1995;55(17):3825–3834
- l-Lysine effectively blocks renal uptake of 125I- or 99mTc-labeled anti-Tac disulfide-stabilized Fv fragment. Cancer Res. 1996;56(16):3788–3795
- Comparative biodistribution of indium- and yttrium-labeled B3 monoclonal antibody conjugated to either 2-(p-SCN-Bz)-6-methyl-DTPA (1B4M-DTPA) or 2-(p-SCN-Bz)-1,4,7,10-tetraazacyclododecane tetraacetic acid (2B-DOTA). Eur J Nucl Med. 1994;21(7):640–646
- Evaluation of the serum stability and in vivo biodistribution of CHX-DTPA and other ligands for yttrium labeling of monoclonal antibodies. J Nucl Med. 1994;35(5):882–889
- Radioimmunotherapy of A431 xenografted mice with pretargeted B3 antibody-streptavidin and 90Y-labeled 1,4,7,10-tetraazacyclododecane-N,N′,Nʺ,Nʺ′-tetraacetic acid (DOTA)-biotin. Cancer Res. 2002;62(20):5755–5760
- Semi-automated 86Y purification using a three-column system. Nucl Med Biol. 2004;31(2):297–301
- Pretargeted alpha emitting radioimmunotherapy using 213Bi 1,4,7,10-tetraazacyclododecane-N,N′,Nʺ,Nʺ′-tetraacetic acid-biotin. Clin Cancer Res. 2004;10(9):3137–3146
- Pretargeted radioimmunotherapy of mesothelin-expressing cancer using a tetravalent single-chain Fv-streptavidin fusion protein. J Nucl Med. 2005;46(7):1201–1209
- Synthesis and biodistribution of 99mTc(CO)3-tridentate-labeled integrin antagonist in tumor bearing mice. J Labelled Compd Radiopharm. 2005;48(S1):S290
- Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography. Cancer Res. 2001;61(5):1781–1785
- Two-step methodology for high-yield routine radiohalogenation of peptides: 18F-labeled RGD and octreotide analogs. J Nucl Med. 2004;45(5):892–902
- Dual optical and nuclear imaging in human melanoma xenografts using a single targeted imaging probe. Nucl Med Biol. 2006;33(3):349–358
- [99mTc]HYNIC-RGD for imaging integrin alpha(v)beta(3) expression. Nucl Med Biol. 2006;33(8):945–952
PII: S0969-8051(07)00041-8
doi: 10.1016/j.nucmedbio.2007.02.002
© 2007 Elsevier Inc. All rights reserved.
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Nuclear Medicine and Biology
Volume 34, Issue 4
, Pages 363-370
, May 2007
