In vitro and in vivo evaluation of [11C]MPEPy as a potential PET ligand for mGlu5 receptors

Severance, Alin J.; Parsey, Ramin V.; Kumar, J.S. Dileep; Underwood, Mark D.; Arango, Victoria; Majo, Vattoly J.; Prabhakaran, Jaya; Simpson, Norman R.; Van Heertum, Ronald L.; Mann, J. John

doi:10.1016/j.nucmedbio.2006.09.007

« Previous Next »Nuclear Medicine and Biology
Volume 33, Issue 8 , Pages 1021-1027, November 2006

In vitro and in vivo evaluation of [¹¹C]MPEPy as a potential PET ligand for mGlu₅ receptors

Alin J. Severance
- Division of Brain Imaging, Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
Ramin V. Parsey
- Department of Psychiatry, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
- Division of Brain Imaging, Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
- Corresponding author. New York State Psychiatric Institute, Box #42, New York, NY 10032, USA. Tel.: +1 212 543 6101; fax: +1 212 543 6017.
J.S. Dileep Kumar
- Department of Psychiatry, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
- Division of Brain Imaging, Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
Mark D. Underwood
- Department of Psychiatry, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
- Division of Brain Imaging, Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
Victoria Arango
- Department of Psychiatry, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
- Division of Brain Imaging, Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
Vattoly J. Majo
- Department of Psychiatry, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Jaya Prabhakaran
- Department of Psychiatry, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Norman R. Simpson
- Department of Radiology, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Ronald L. Van Heertum
- Department of Radiology, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
J. John Mann
- Department of Psychiatry, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
- Department of Radiology, New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
- Division of Brain Imaging, Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA