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Nuclear Medicine and Biology
Volume 33, Issue 6
, Pages 723-733
, August 2006
Reducing renal uptake of 90Y- and 177Lu-labeled alpha-melanocyte stimulating hormone peptide analogues
References
- Radiotherapy and dosimetry of 64Cu-TETA-Tyr3-octreotate in a somatostatin receptor-positive, tumor-bearing rat model. Clin Cancer Res. 1999;5:3608–3616
- Receptor mediated radiotherapy with 90Y-DOTA-d-Phe1-Tyr3-octreotide. Eur J Nucl Med. 2001;28:426–434
- Somatostatin receptor-targeted radionuclide therapy of tumors: preclinical and clinical findings. Semin Nucl Med. 2002;32:133–140
- . Therapeutic efficacy of a 188Re labeled α-melanocyte stimulating hormone peptide analogue in murine and human melanoma-bearing mouse models. J Nucl Med. 2005;46:121–129
- . Therapeutic radionuclides: production and decay property consideration. J Nucl Med. 1991;32:174–185
- . Studies on renal tubular protein reabsorption: partial and near complete inhibition by certain amino acids. Scand J Clin Lab Invest. 1977;37:477–486
- . The renal handling of amino acids and oligopeptides. Physiol Rev. 1988;68:912–986
- . Renal filtration, transport, and metabolism of low molecular weight proteins: a review. Kidney Int. 1979;16:251–270
- Identification of the soluble in vivo metabolites of indium-111-diethylenetriaminepentaacetic acid-d-Phe1-octreotide. Bioconjug Chem. 1998;9:192–200
- . Intracellular metabolism of indium-111-DTPA-labeled receptor targeted proteins. J Nucl Med. 1993;34:1728–1738
- . Metabolism of receptor targeted 111In-DTPA-glycoproteins: identification of 111In-DTPA-ε-lysine as the primary metabolic and excretory product. Nucl Med Biol. 1994;21:1023–1034
- Identification of metabolites of 111In-diethylenetriaminepentaacetic acid-monoclonal antibodies and antibody fragments in vivo. Cancer Res (suppl). 1995;55:5714s–5720s
- Chemical design of radiolabeled antibody fragments for low renal radioactivity levels. Cancer Res. 1999;59:128–134
- The pharmacokinetic characteristics of glycolated humanized anti-Tac Fabs are determined by their isoelectric points. Cancer Res. 1999;59:422–430
- Reduction of the renal uptake of radiolabeled monoclonal antibody fragments by cationic amino acids and their derivatives. Cancer Res. 1995;55:3825–3834
- Reduction of renal uptake of monoclonal antibody fragments by amino acid infusion. J Nucl Med. 1996;37:829–833
- d-Lysine reduction of indium-111 octreotide and yttrium-90 octreotide renal uptake. J Nucl Med. 1997;38:1929–1933
- . Safe and effective inhibition of renal uptake of radiolabelled octreotide by a combination of lysine and arginine. Eur J Nucl Med Mol Imaging. 2003;30:9–15
- Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer Melanoma Staging System. J Clin Oncol. 2001;19:3622–3634
- . Design and characterization of α-melanotropin peptide analogs cyclized through rhenium and technetium metal coordination. Proc Natl Acad Sci U S A. 1998;95:12814–12818
- . Melanoma-targeting properties of 99mtechnetium-labeled cyclic α-melanocyte-stimulating hormone peptide analogues. Cancer Res. 2000;60:5649–5658
- . In vivo evaluation of 188Re-labeled alpha-melanocyte stimulating hormone peptide analogs for melanoma therapy. Int J Cancer. 2002;101:480–487
- . Evaluation of the human melanoma targeting properties of radiolabeled alpha-melanocyte stimulating hormone peptide analogues. Bioconjug Chem. 2003;14:1177–1184
- Evaluation of an 111In-DOTA-rhenium cyclized α-MSH analog: a novel cyclic-peptide analog with improved tumor-targeting properties. J Nucl Med. 2001;42:1847–1855
- . Modification of the structure of a metallopeptide: synthesis and biological evaluation of 111In-labeled DOTA-conjugated rhenium-cyclized α-MSH analogues. J Med Chem. 2002;45:3048–3056
- . Tumor targeting properties of 90Y and 177Lu labeled alpha-melanocyte stimulating hormone peptide analogues in a murine melanoma model. Nucl Med Biol. 2005;32:485–493
- . Vehicles, chelators, and radionuclides: choosing the “building blocks” of an effective therapeutic radioimmunoconjugate. Bioconjug Chem. 1996;7:165–179
- . The somatostatin receptor-targeted radiotherapeutic [90Y-DOTA-dPhe1, Tyr3]octreotide (90Y-SMT 487) eradicates experimental rat pancreatic CA20948 tumors. Eur J Nucl Med. 1998;25:668–674
- . DTPA-coupled antibodies labeled with yttrium-90. J Nucl Med. 1985;26:503–509
- A mouse model for calculating cross-organ beta doses from yttrium-90-labeled immunoconjugates. Cancer. 1994;73(Suppl):951–957
- . Application of the cross-organ beta dose method for tissue dosimetry in tumor-bearing mice treated with a 90Y-labeled immunoconjugate. Cancer. 1994;73(Suppl):958–965
- . Antibody-targeted radiation cancer therapy. Nat Rev Drug Discov. 2004;3:488–499
- . Use of polyglutamic acids to reduce uptake of radiometal-labeled minigastrin in the kidneys. J Nucl Med. 2005;46:1012–1015
- . Uptake of [111In-DTPA0]octreotide in the rat kidney is inhibited by colchicine and not by fructose. J Nucl Med. 2004;45:709–713
- Megalin is essential for renal proximal tubule reabsorption of 111In-DTPA-octreotide. J Nucl Med. 2005;46:1696–1700
- Uptake kinetics of the somatostatin receptor ligand [86Y]DOTA-dPhe1-Tyr3-octreotide ([86Y]SMT487) using positron emission tomography in nonhuman primates and calculation of radiation doses of the 90Y-labeled analogue. Eur J Nucl Med. 1999;26:358–366
- . Imaging of melanoma using 64Cu- and 86Y-DOTA-ReCCMSH(Arg11), a cyclized peptide analogue of α-MSH. J Med Chem. 2005;48:2985–2992
- Melanoma therapy via peptide-targeted α-radiation. Clin Cancer Res. 2005;11:5616–5621
- Somatostatin receptor-targeted radionuclide therapy of tumors: preclinical and clinical findings. Semin Nucl Med. 2002;32:133–140
PII: S0969-8051(06)00106-5
doi: 10.1016/j.nucmedbio.2006.06.005
© 2006 Elsevier Inc. All rights reserved.
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Nuclear Medicine and Biology
Volume 33, Issue 6
, Pages 723-733
, August 2006
