Nuclear Medicine and Biology
Volume 33, Issue 6 , Pages 695-704 , August 2006

Chiral dimethylamine flutamide derivatives—modeling, synthesis, androgen receptor affinities and carbon-11 labeling

  • Orit Jacobson

      Affiliations

    • Department of Medical Biophysics and Nuclear Medicine, The Hebrew University of Jerusalem, Hadassah Hospital, Jerusalem 91120, Israel
  • ,
  • Desideriu Laky

      Affiliations

    • Department of Medical Biophysics and Nuclear Medicine, The Hebrew University of Jerusalem, Hadassah Hospital, Jerusalem 91120, Israel
  • ,
  • Kathryn E. Carlson

      Affiliations

    • Department of Chemistry, University of Illinois, Urbana, IL 61801, USA
  • ,
  • Sharona Elgavish

      Affiliations

    • Bioinformatics Unit, The Hebrew University of Jerusalem, Jerusalem 91120, Israel
  • ,
  • Michael Gozin

      Affiliations

    • School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel
  • ,
  • Einat Even-Sapir

      Affiliations

    • Department of Nuclear Medicine, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv 64239, Israel
  • ,
  • Ilan Leibovitc

      Affiliations

    • Department of Urology, Meir Medical Center, Sackler School of Medicine, Tel Aviv University, Kfar Sava 44281, Israel
  • ,
  • Mordechai Gutman

      Affiliations

    • Department of Surgery A, Sapir Medical Center, Sackler School of Medicine, Tel Aviv University, Kfar Sava 44281, Israel
  • ,
  • Roland Chisin

      Affiliations

    • Department of Medical Biophysics and Nuclear Medicine, The Hebrew University of Jerusalem, Hadassah Hospital, Jerusalem 91120, Israel
  • ,
  • John A. Katzenellenbogen

      Affiliations

    • Department of Chemistry, University of Illinois, Urbana, IL 61801, USA
  • ,
  • Eyal Mishani

      Affiliations

    • Department of Medical Biophysics and Nuclear Medicine, The Hebrew University of Jerusalem, Hadassah Hospital, Jerusalem 91120, Israel
    • Corresponding Author InformationCorresponding author. Tel.: +972 2 677931; fax: +972 2 6421203.

Received 16 April 2006 ,Revised 28 May 2006 ,Accepted 28 May 2006.

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PII: S0969-8051(06)00100-4

doi: 10.1016/j.nucmedbio.2006.05.010

Nuclear Medicine and Biology
Volume 33, Issue 6 , Pages 695-704 , August 2006