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Nuclear Medicine and Biology
Volume 33, Issue 5
, Pages 635-643
, July 2006
99mTc-labeled annexin V fragments: a potential SPECT radiopharmaceutical for imaging cell death
References
- . Tumor radiosensitivity and apoptosis. Expt Cell Res. 1999;248:10–17
- . Apoptosis, graft rejection and transplantation tolerance. Transplantation. 1998;65:869–875
- . Apoptosis and antiapoptotic mechanisms in stroke. Cell Tissue Res. 2000;301:173–187
- . Apoptosis in the pathogenesis and treatment of disease. Science. 1995;267:1456–1462
- . Apoptosis and morphology in mouse embryos by confocal laser scanning microscopy. Methods. 1999;18:473–480
- . 1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis. Nat Med. 1999;5:1323–1327
- . Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol. 1992;148:2207–2216
- . Human placental anticoagulant protein: isolation and characterization. Biochemistry. 1987;26:5572–5578
- . Isolation and partial purification of a novel anticoagulant from arteries of human umbilical cord. Eur J Biochem. 1985;151:625–629
- . Cloning and expression of cDNA for human vascular anticoagulant, a Ca2+-dependent phospholipid-binding protein. Eur J Biochem. 1988;174:585–592
- . A simplified method for preparation of 99mTc-annexin V and its biologic evaluation for in vivo imaging of apoptosis after photodynamic therapy. J Nucl Med. 2003;44:650–656
- . Chemotherapy induced change in 99mTc HYNIC-annexin V uptake as an early predictor of response to platinum therapy in advanced non-small cell lung cancer. J Nucl Med. 2004;45:36P
- . Imaging cell death with radiolabeled annexin V in an experimental model of rheumatoid arthritis. J Nucl Med. 2002;43:1359–1365
- . Imaging cyclophosphamide-induced intramedullary apoptosis in rats using 99mTc radiolabeled annexin V. J Nucl Med. 2001;42:309–316
- . Synthesis and evaluation of a 18F labeled recombinant annexin-V derivative for identification and quantification of apoptotic cells with PET. Appl Radiat Isot. 2003;58:201–207
- . Preparation of F-18 labeled annexin V: a potential PET radiopharmaceutical for imaging cell death. Nucl Med Biol. 2004;31:747–752
- . 94mTc and 64Cu labeled annexin V positron-emitting radiopharmaceuticals. J Label Compd Radiopharm. 2003;46:S1–S4
- Functional comparison of annexin V analogues labeled indirectly and directly with iodine 124. Nucl Med Biol. 2005;32:403–413
- Iodine-124 labeled annexin-V as a potential radiotracer to study apoptosis using positron emission tomography. Appl Radiat Isot. 2003;58:55–62
- . Synthesis and in vitro evaluation of 123I-labeled human recombinant annexin V. Biomol Eng. 2001;17:51–53
- Iodination of annexin V for imaging apoptosis. J Nucl Med. 2002;43:671–677
- In vivo detection and imaging of phophatidylserine expression during programmed cell death. Proc Natl Acad Sci U S A. 1998;95:6349–6354
- Visualization of cell death in vivo in patients with acute myocardial infarction. Lancet. 2000;356:209–212
- Imaging apoptosis in vivo using 124I annexin V and PET. Nucl Med Biol. 2005;32:395–402
- Imaging of apoptosis (programmed cell death) with 99mTc annexin V. J. Nucl Med. 1999;40:184–191
- Past present and future of annexin A5: from protein discovery to clinical application. J Nucl Med. 2005;46:2035–2050
- . Calcium dependent annexin binding to phospholipids: stoichiometry, specificity and role of negative charge. Biochemistry. 1993;32:11711–11721
- . Annexins: the problem of assessing the biological role for gene family multifunctional calcium- and phospholipid-binding proteins. Biochim Biophys Acta. 1994;1197:63–93
- . Characterization of two distinct Ca2+ dependent phospholipid binding proteins of 68 kDa isolation from placenta. J Biol Chem. 1989;264:17222–17230
- . A dimeric form of lipocortin-1 in human placenta. Biochem J. 1989;263:97–103
- . Scopinaro, peptide radiopharmaceuticals for diagnosis and therapy. Eur J Nucl Med. 2001;28:1555–1565
- . Development of annexin V fragments for labeling with 99mTc. Report 2nd research coordination meeting on “Development of 99mTc based small biomolecules using novel 99mTc cores”. Vienna: IAEA; 2004;
- . In: International symposium on radiochemistry and radiation chemistry, AR-19, 1-2, Bhabha Atomic Research Center, Bombay, India. 2000;
- . Solid phase peptide synthesis. 2nd ed. Rockford (IL): Pierce Chemical Company; 1984;
- Structure–activity on the Phe side chain arrangement of endomorphins using conformationally constrained analogues. J Med Chem. 2004;447:735–743
- . The preparation of Merrifield-resins through total esterification with cesium salts. Helv Chim Acta. 1973;56:1476–1482
- . A novel organometallic aqua complex of technetium for the labeling of biomolecules: synthesis of [Tc-99m (OH2)3(CO)3]+ from [(TcO4)-Tc-99m] in aqueous solution and its reaction with a bifunctional ligand. J Am Chem Soc. 1998;120:7987–7988
- The ApoCorrect assay: a novel, rapid method to determine the biological functionality of radiolabeled and fluorescent annexin A5. Anal Biochem. 2004;327:126–134
- Safety, biodistribution, and dosimetry of 99mTc-HYNIC-annexin V, a novel human recombinant annexin V for human application. J Nucl Med. 2003;44:947–952
- Iodine-124 labelled annexin V as a potential radiotracer to study apoptosis using positron emission tomography. Appl Radiat Isot. 2003;58:55–62
- A novel approach to the high specific activity labeling of small peptides with the technetium-99m fragment [99mTc(N)(PXP)]2+ (PXP=diphosphine ligand). Bioconjug Chem. 2001;12:1035–1042
- . Technetium-99m labeled receptor-specific small molecule radiopharmaceuticals: recent developments and encouraging results. Nucl Med Biol. 1997;24:485–498
- . The biomedical chemistry of technetium and rhenium. Chem Soc Rev. 1998;27(Suppl):43–55
- . Development of annexin V mutants suitable for labeling with Tc (i)-carbonyl complex. Bioconjug Chem. 2002;13:1119–1123
- . Apoptosis in the pathogenesis and treatment of disease. Science. 1995;267:1456–1462
- . Nuclear medicine applications in molecular imaging. J Magn Reson Imaging. 2002;16:352–361
PII: S0969-8051(06)00094-1
doi: 10.1016/j.nucmedbio.2006.05.002
© 2006 Elsevier Inc. All rights reserved.
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Nuclear Medicine and Biology
Volume 33, Issue 5
, Pages 635-643
, July 2006
