Nuclear Medicine and Biology
Volume 33, Issue 3 , Pages 295-304, April 2006

Nicotinic α4β2 receptor imaging agents:

Part II. Synthesis and biological evaluation of 2-[18F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine (18F-nifene) in rodents and imaging by PET in nonhuman primate

Presented in part at the 52nd Annual Society of Nuclear Medicine Meeting, Toronto, Canada, June 18–23, 2005.

  • Rama Pichika

      Affiliations

    • Brain Imaging Center, Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697-3960, USA
    • ,
  • Balasubramaniam Easwaramoorthy

      Affiliations

    • Brain Imaging Center, Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697-3960, USA
    • ,
  • Daphne Collins

      Affiliations

    • Brain Imaging Center, Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697-3960, USA
    • ,
  • Bradley T. Christian

      Affiliations

    • Department of Nuclear Medicine, Kettering Medical Center, Dayton, OH 45429, USA
    • ,
  • Bingzhi Shi

      Affiliations

    • Department of Nuclear Medicine, Kettering Medical Center, Dayton, OH 45429, USA
    • ,
  • Tanjore K. Narayanan

      Affiliations

    • Department of Nuclear Medicine, Kettering Medical Center, Dayton, OH 45429, USA
    • ,
  • Steven G. Potkin

      Affiliations

    • Brain Imaging Center, Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697-3960, USA
    • ,
  • Jogeshwar Mukherjee

      Affiliations

    • Brain Imaging Center, Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697-3960, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 949 824 2018; fax: +1 949 824 4144.

Received 18 December 2005; received in revised form 21 December 2005; accepted 29 December 2005.

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PII: S0969-8051(06)00003-5

doi:10.1016/j.nucmedbio.2005.12.017

Nuclear Medicine and Biology
Volume 33, Issue 3 , Pages 295-304, April 2006

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